Vanderhyden Lab

Barbara Vanderhyden profile picture

Contact Information

Barbara Vanderhyden, PhD
613-737-7700 ext. 70330
bvanderhyden@ohri.ca

Ottawa Hospital Research Institute
Centre for Cancer Therapeutics
501 Smyth Road
Box 926
Ottawa, ON K1H 8L6

ORCID logo https://orcid.org/0000-0002-7644-7189

Publications

Selected Publications

Cook DP, Galpin KJC, Rodriguez GM, Shakfa N, Wilson-Sanchez J, Echaibi M, Pereira M, Matuszewska K, Haagsma J, Murshed H, Cudmore AO, Macdonald E, Tone A, Shepherd TG, Petrik JP, Koti M, and BC Vanderhyden (2023). Comparative analysis of syngeneic mouse models of high-grade serous ovarian cancer. Commun. Biol. 6: 1152. https://doi.org/10.1038/s42003-023-05529-z.

Landry DA, Yakubovich E, Cook DP, Fasih S, Upham J and Vanderhyden BC (2022). Metformin prevents age-associated ovarian fibrosis by modulating the immune landscape in female mice. Science Advances 8(35):eabq1475. doi: 10.1126/sciadv.abq1475

Rodriguez GM, Galpin KJC, Cook DP, Yakubovich E, Maranda V, Macdonald E, Wilson-Sanchez J, Thomas AL, Burdette JE, and BC Vanderhyden (2022). The tumor immune profile of murine ovarian cancer models: An essential tool for ovarian cancer immunotherapy research. Cancer Res. Commun. 2: 417-433.

Cook DP and BC Vanderhyden (2022). Transcriptional census of epithelial-mesenchymal plasticity in cancer. Science Advances 8(1):eabi7640. doi: 10.1126/sciadv.abi7640.

Abedini A, Landry DA, Macaulay AD, Vaishnav H, Parbhakar A, Ibrahim D, Salehi R, Maranda V, Macdonald E and BC Vanderhyden (2022). SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility. Biol Reprod. 108(2):279-291. doi: 10.1093/biolre/ioac209.

David S, Plante A, Dallaire F, Tremblay J-P, Sheehy G, Macdonald E, Forrest L, Daneshmand M, Trudel D, Wilson BC, Hopkins L, Murugkar S, Vanderhyden B, and F Leblond (2022). Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy. J. Biophotonics 15(2): e202100198. doi.org/10.1002/jbio.202100198.

Carter LE, DP Cook, CW McCloskey, MA Grondin, DA Landry, T Dang, O Collins, LF Gamwell, HA Dempster, BC Vanderhyden (2021). Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium. Communications Biology, 4(1): 527. doi: 10.1038/s42003-021-02045-w.

Landry DA, HT Vaishnav, BC Vanderhyden (2020). The significance of ovarian fibrosis. Oncotarget 11: 4366-4370. doi: 10.18632/oncotarget.27822.

Robineau-Charette P, Grynspan D, Benton SJ, Gaudet J, Cox BJ, Vanderhyden BC, Bainbridge SA (2020). Fibrinogen-like protein 2-associated transcriptional and histopathological features of immunological preeclampsia. Hypertension 76: 910-921.

Abedini A, C Sayed, LE Carter, D Boerboom, BC. Vanderhyden (2020). Non-canonical WNT5a regulates epithelial-to-mesenchymal transition in the mouse ovarian surface epithelium. Sci. Reports 10: 9695.

Cook DP and BC Vanderhyden (2020). Context specificity of the EMT transcriptional response. Nat. Commun. 11: 2142. doi: 10.1038/s41467-020-16066-2.

All Other Publications

Al-Hujaily EM, Y Tang, D-S Yao, E Carmona, K Garson and BC Vanderhyden (2015). Divergent roles of PAX2 in the etiology and progression of ovarian cancer. Cancer Prev. Res. 8: 1163-1173.

Garson K and Vanderhyden BC (2015). Epithelial ovarian cancer stem cells: underlying complexity of a simple paradigm. Reproduction. 149: 59-70

McCloskey CW, Goldberg RL, Carter LE, Gamwell LF, Al-Hujaily EM, Collins O, Macdonald EA, Garson K, Daneshmand M, Carmona E and Vanderhyden BC (2014). A new spontaneously transformed syngeneic model of high-grade serous ovarian cancer with a tumor-initiating cell population. Front Oncol. 4: 53.

Laviolette LA, Hodgkinson KM, Minhas N, Perez-Iratxeta C, Vanderhyden BC (2014). 17β-estradiol upregulates GREB1 and accelerates ovarian tumour progression in vivo. Int. J. Cancer. Jan 27. doi: 10.1002/ijc.28741. 

Gamwell LF, M Merziotis, K Gambaro, SL Arcand, V Snoulten, C Davis, JA Squire, DL Huntsman, PN Tonin and BC Vanderhyden (2013). Characterization of a small cell ovarian cancer cell line: Genomic anomalies and responsiveness to therapeutics. Orphanet Journal of Rare Diseases 8: 33. 

Pépin D, Paradis F, Perez-Iratxeta C, Picketts DJ, Vanderhyden BC (2013).  The imitation switch ATPase Snf2l is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells.  Biol. Reprod.. 88: 142. doi: 10.1095/biolreprod.112.105742.

Listings from The Ottawa Hospital Library

This lists the 5 most recent publications in The Ottawa Hospital's Library database from this lab.This database only starts tracking a researcher's publications once they start working at the Ottawa Hospital Research Institute.
More publications may be available in The Ottawa Hospital Library database.

PubMed Listings

For more publications use this PubMed ID link.