Publications

Book Chapters

  1. Alam MB, Jones G, Seely AJ, Poehlman W, Kamath MV. Heart rate variability in the intensive care unit. Heart rate variability (HRV) signal analysis. CRC Press; 2013. p. 203.
  2. Herry CL, Green GC, Bravi A, Seely AJE. Continuous Multiorgan Variability Monitoring in Critically Ill Patients: Complexity Science at the Bedside. Handbook of Systems and Complexity in Health. Springer New York; 2013. p. 467-81.

Journal Articles

  1. Seely AJE. Data intelligence is the future of monitoring. J. Clin. Monit. Comput. 2014;Feb 5
  2. Flouris AD, Bravi A, Wright-Beatty HE, Green G, Seely AJE, Keeny GP. Heart rate variability during exertional heat stress: effects of heat production and treatment Eur. J. Appl. Physiol. 2014;Jan 5
  3. Seely AJE. Embracing the certainty of uncertainty: implications for health care and research. Perspect. Biol. Med. 2013;Winter;56(1):65-77
  4. Bravi A, Green G, Herry C, Wright H, Longtin A, Kenny G, Seely AJE. Do physiological and pathological stresses produce different changes in heart rate variability? Frontiers in physiology 2013;4
  5. Green GC, Bradley BD, Bravi A, Seely A. Continuous multiorgan variability analysis to track severity of organ failure in critically ill patients. J. Crit. Care 2013 Oct;28(5):879.e1-879.e11
  6. Barrera-Ramirez J, Bravi A, Kenny G, Green G, Seely AJE. Comparison of heart and respiratory rate variability measures using an intermittent incremental submaximal exercise model. Appl. Physiol. Nutr. Metab. 2013:1-9
  7. Bradley BD, Green G, Ramsay T, Seely AJE. Impact of sedation and organ failure on continuous heart and respiratory rate variability monitoring in critically ill patients: A pilot study*. Crit. Care Med. 2013 Feb;41(2):433-44.
  8. Buchan CA, Bravi A, Seely AJE. Variability analysis and the diagnosis, management, and treatment of sepsis. Curr Infect Dis Rep. 2012 Oct;14(5):512-21.
  9. Bradley B, Green GC, Batkin I, Seely AJE. Feasibility of continuous multiorgan variability analysis in the intensive care unit. J. Crit. Care. 2012 Apr;27(2):218.e9-20.
  10. Seely AJE, Macklem P. Fractal variability: an emergent property of complex dissipative systems. Chaos. 2012 Mar;22(1):013108.
  11. Armstrong RG, Ahmad S, Seely AJ, Kenny GP. Heart rate variability and baroreceptor sensitivity following exercise-induced hyperthermia in endurance trained men. Eur. J. Appl. Physiol. 2012 Feb;112(2):501-11.
  12. Seely AJE, Macklem P. Fractal variability: An emergent property of complex dissipative systems. Chaos. 2012 Jan 19;22(1):013108-013108-7.
  13. Bravi A, Green G, Longtin A, Seely AJE. Monitoring and identification of sepsis development through a composite measure of heart rate variability. PLoS ONE. 2012;7(9):e45666.
  14. Kellett J, Li M, Rasool S, Green GC, Seely A. Comparison of the heart and breathing rate of acutely ill medical patients recorded by nursing staff with those measured over 5 min by a piezoelectric belt and ECG monitor at the time of admission to hospital. Resuscitation. 2011 Nov;82(11):1381-6.
  15. Seely AJE. Complexity at the bedside. J. Crit. Care. 2011 Jun;26(3):323-4. [Editorial]
  16. Armstrong RG, Kenny GP, Green G, Seely AJE. Diurnal variation in heart rate variability before and after maximal exercise testing. Chronobiol. Int. 2011 May;28(4):344-51.
  17. Bravi A, Longtin A, Seely AJE. Review and classification of variability analysis techniques with clinical applications. Biomed Eng Online. 2011;10:90.
  18. Armstrong RG, Seely AJ, Kilby D, Journeay WS, Kenny GP. Cardiovascular and thermal responses to repeated head-up tilts following exercise-induced heat stress. Aviat Space Environ Med. 2010 Jul;81(7):646-53.
  19. Macklem PT, Seely A. Towards a definition of life. Perspect. Biol. Med. 2010;53(3):330-40.
  20. Ahmad S, Tejuja A, Newman KD, Zarychanski R, Seely AJ. Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection. Crit Care. 2009 Nov 24;13(6):232.
  21. Ahmad S, Ramsay T, Huebsch L, Flanagan S, McDiarmid S, Batkin I, et al. Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults. PLoS ONE. 2009;4(8):e6642.
  22. Seely AJE. Life,emergence and entropy production. J. Appl. Physiol. 2008 Jun;104(6):1850; author reply 1851. [Commentary]
  23. Seely AJE. Heart rate variability and infection: diagnosis, prognosis, and prediction. J. Crit. Care. 2006 Sep;21(3):286-9.
  24. Seely AJ, Macklem PT. Complex systems and the technology of variability analysis. Crit Care. 2004 Sep 22;8(6):R367.

Conference papers

  1. Bravi A, Herry C, Seely A, Longtin A. What is the meaning of a measure of heart rate variability. J. Crit. Care. 2013;28(6):e38-e39.
  2. Durosier LD, Xu A, Matushewski B, Cao M, Herry C, Batkin I, Seely AJE, Ross MG, Richardson BS, Frasch MG. Neural signature of cerebral activity of the fetal cholinergic anti-inflammatory pathway derived from heart rate variability. FASEB Journal 2013;27.
  3. Durosier LD, Cao M, Herry C, Batkin I, Seely AJE, Burns P, Fecteau G, Desrochers A, Frasch MG. A signature of fetal systemic inflammatory response in the pattern of heart rate variability measures matrix: a prospective study in fetal sheep model of lipopolysaccharide (LPS)-induced sepsis. FASEB Journal 2013;27.
  4. Durosier LD, Cao M, Batkin I, Matushewski BJ, Keenliside L, Herry C, et al. Continuous multivariate electronic fetal monitoring during labor detects early onset of acidemia: Prospective study in fetalsheep model. J. Crit. Care. 2013;28(1):e5-e6.
  5. Durosier DL, Siontas D, Cao M, Herry C, Green G, Batkin I, et al. The timing and degree of fetal systemic and cerebral inflammatory responses correlate with a subset of heart rate variability measures: Evidence of cholinergic anti-inflammatory pathway activation in sepsis. J. Crit. Care. 2013;28(1):e25-e25.
  6. Buchan CA, Bravi A, Seely AJE. Variability analysis and the diagnosis, management and treatment of sepsis. J. Crit. Care. 2013;28(1):e22-e23.
  7. Bravi A, Herry C, Townsend D, Green G, Ramsay T, Longtin A, et al. Towards the identification of independent measures of heart rate variability. J. Crit. Care. 2013;28(1):e16-e16.
  8. Bravi A, Green G, Longtin A, Seely AJE. Development of a composite variability metric for clinical application. J. Crit. Care. 2012 Jun;27(3):e2.
  9. Famili FA, Liu Z, Bravi A, Seely AJE. Searching for patterns in clinical data - Choosing the right data mining approach. Proceedings of the 1st International Workshop on Artificial Intelligence and NetMedicine [Internet]. Montpellier, France; 2012.
  10. Bravi A, Green G, Longtin A, Kenny GP, Seely AJE. Differential patterns of change in heart rate variability during physiological and pathological stress. Proceedings of the 7th ESCGCO. KazimierzDolny,Poland; 2012
  11. Durosier D, Cao M, Green G, Batkin I, Seely A, Richardson BS, et al. Continuous fetal heart rate variability (fHRV) analysis allows for early detection of hypoxic-acidemia near-term. Reprod Sci. 2012 Mar;19(3 Suppl):253A.
  12. Bravi A, Green G, Longtin A, Seely AJE. The problem of parameter estimation within variability analysis: Generalization through optimization. J. Crit. Care. 2012;27(3):e6-e6.
  13. Arnold R, Green G, Bravi A, Hollenberg S, Seely A. Impaired heart rate variability predicts clinical deterioration and progressive organ failure in emergency department sepsis patients. Crit Care. 2012;16(Suppl 1):P37.
  14. Seely AJE, Green GC, Bravi A. Continuous Multiorgan Variability monitoring in critically ill patients: Complexity science at the bedside. 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society,EMBC. 2011. p. 5503 -5506.
  15. Arnold RC, Lundy DJ, Glaspey L, Green G, Seely AJE. Heart rate variability in the early resuscitation of septic shock. Crit Care. 2009 Nov 11;13(Suppl 4):P50.