Dilworth Lab

Jeff Dilworth profile picture

Contact Information

Jeff Dilworth, PhD
613-737-8899 ext. 70339


Selected Publications

H. Faralli, C. Wang, A. Benyoucef, S. Sebastian, L. Zhuang, A. Chu, C. Palii, C. Liu, B. Camellato, M. Brand, K. Ge, and F.J. Dilworth. H3K27-demethylase activity of UTX/KDM6A is essential for skeletal muscle regeneration. Journal of Clinical Investigation 126: 1555-1565, 2016.

K. Singh, M. Cassano, E. Planet, S.Sebastian, S.M. Jang, G. Sohi, J. Choi, H.D. Youn, F.J. Dilworth*, and D. Trono*. KAP1 functions as a phosphorylation-inducible activator of MyoD function during skeletal muscle differentiation. Genes & Dev 29: 513-525, 2015. *Co-corresponding authors

S. Sebastian, H. Faralli, Z. Yao, P. Rakopoulos, C. Palii, Y. Cao, K. Singh, Q-C. Liu, A. Chu, A. Aziz, M. Brand, S.J. Tapscott, and F.J. Dilworth. Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation. Genes & Dev 27: 1247-1259, 2013.

Q-C. Liu, X. Zha, H. Faralli, H. Yin, C. Louis-Jeune, E. Perdiguero, E. Pranckeviciene, P. Munoz-Canoves, M. Rudnicki, M. Brand, C. Perez-Iratxeta, and F.J. Dilworth. Comparative expression profiling identifies differential roles for Myogenin and p38a MAPK signaling in myogenesis. J Mol Cell Biol. 4 : 386-397, 2012.

S. Seenundun, S. Rampalli, Q-C. Liu, A. Aziz, C. Palii, S.H. Hong, A. Blais, M. Brand, K. Ge, F.J. Dilworth. UTX-mediated demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO Journal 29: 1401-1411, 2010.

S. Rampalli, L. Li, E. Mak, K. Ge, M. Brand, S.J. Tapscott, and F.J. Dilworth. p38 MAPK signaling pathway regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nature Struct Mol Biol 14: 1150-1156, 2007.

PubMed Listings

For more publications use this PubMed ID link.