Dilworth Lab

Jeff Dilworth profile picture

Contact Information

Jeff Dilworth, PhD
613-737-8899 ext. 70339
jdilworth@ohri.ca

Publications

Selected Publications

H. Faralli, C. Wang, A. Benyoucef, S. Sebastian, L. Zhuang, A. Chu, C. Palii, C. Liu, B. Camellato, M. Brand, K. Ge, and F.J. Dilworth. H3K27-demethylase activity of UTX/KDM6A is essential for skeletal muscle regeneration. Journal of Clinical Investigation 126: 1555-1565, 2016.

K. Singh, M. Cassano, E. Planet, S.Sebastian, S.M. Jang, G. Sohi, J. Choi, H.D. Youn, F.J. Dilworth*, and D. Trono*. KAP1 functions as a phosphorylation-inducible activator of MyoD function during skeletal muscle differentiation. Genes & Dev 29: 513-525, 2015. *Co-corresponding authors

S. Sebastian, H. Faralli, Z. Yao, P. Rakopoulos, C. Palii, Y. Cao, K. Singh, Q-C. Liu, A. Chu, A. Aziz, M. Brand, S.J. Tapscott, and F.J. Dilworth. Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation. Genes & Dev 27: 1247-1259, 2013.

Q-C. Liu, X. Zha, H. Faralli, H. Yin, C. Louis-Jeune, E. Perdiguero, E. Pranckeviciene, P. Munoz-Canoves, M. Rudnicki, M. Brand, C. Perez-Iratxeta, and F.J. Dilworth. Comparative expression profiling identifies differential roles for Myogenin and p38a MAPK signaling in myogenesis. J Mol Cell Biol. 4 : 386-397, 2012.

S. Seenundun, S. Rampalli, Q-C. Liu, A. Aziz, C. Palii, S.H. Hong, A. Blais, M. Brand, K. Ge, F.J. Dilworth. UTX-mediated demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO Journal 29: 1401-1411, 2010.

S. Rampalli, L. Li, E. Mak, K. Ge, M. Brand, S.J. Tapscott, and F.J. Dilworth. p38 MAPK signaling pathway regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nature Struct Mol Biol 14: 1150-1156, 2007.

PubMed Listings

For more publications use this PubMed ID link.