Kothary Lab

Rashmi Kothary profile picture

Contact Information

Rashmi Kothary, Ph.D.

Lab Tel: 613-739-6634

Heidi Hickey
Research Administrative Assistant
Tel: 613-737-8899 x72794
Email: hhickey@ohri.ca

What We Do

Our laboratory is interested in understanding the mechanisms which maintain/alter muscle and nervous system integrity. In parallel, we are assessing ways to alleviate the pathology of neuromuscular diseases.

Selected Publications

Ryan, S.D., Bhanot, K., Ferrier, A., De Repentigny, Y., Chu, A., Blais, A., and Kothary, R.(2012). Microtubule stability, Golgi organization, and transport flux require dystonin-a2/MAP1B interaction. J. Cell Biol. 196, 727-742.

Bowerman, M., Swoboda, K.J., Michalski, J-P., Wang, G-S., Reeks, C., Beauvais, A., Murphy, K., Woulfe, J., Screaton, R.A., Scott, F.W., and Kothary, R. (2012). Glucose metabolism and pancreatic developmental defects in mice and humans with Spinal Muscular Atrophy. Annals Neurol. 72, 256-68.

*O'Meara, R.*Michalski, J.P., Anderson, C., Bhanot, K., Rippstein, P., and Kothary, R. (2013). Integrin-linked kinase regulates process extension in oligodendrocytes via control of actin cytoskeletal dynamics. J. Neurosci.33, 9781-93.

*Bowerman, M., *Michalski, J-P., Beauvais, A., Murray, L.M., De Repentigny, Y., and Kothary, R. (2014). Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical Spinal Muscular Atrophy neuromuscular pathology. Hum. Mol. Gen.23, 3432-3444.

Boyer, J.G., Deguise, M-O., Murray, L.M., Yazdani, A., De Repentigny, Y., Boudreau-Larivière, C.,and Kothary, R. (2014). Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy.Hum. Mol. Gen.23, 4249-4259.

Meet the Kothary Lab