Engineered lung tissue model reveals possible new treatment for lymphangioleiomyomatosis
July 12, 2023 - A research team led by Dr. Bill Stanford has discovered a new class of drugs that may be effective in treating lymphangioleiomyomatosis (LAM). This rare disease is characterized by abnormal cell growth in the lungs which can lead to severe ... |
‘Cord blood cells are priceless for us’
March 1, 2023 - Cord blood donors help fuel Dr. William Stanford’s research and bring hope to leukemia patients |
Lab-grown “mini-kidneys” unlock secrets of a rare disease
July 21, 2022 - Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumours in patients with tuberous sclerosis complex (TSC). |
Researchers at The Ottawa Hospital awarded 19 CIHR grants worth more than $12 million
July 20, 2022 - These projects will advance science and improve health in areas such as cancer, neuroscience, regenerative medicine, autism, Kabuki Syndrome, kidney disease, patient engagement, blood transfusions, sepsis, surgery, anesthesia, plasma donation, ... |
Researchers at The Ottawa Hospital awarded eight grants worth $5 million from the Canadian Institutes of Health Research
August 10, 2021 - These projects will advance science and improve health in areas such as cancer immunotherapy, orthopedic surgery, long-term care, neuromuscular disease, blood clots, vascular disease, aging, kidney disease and Inuit health. |
Using lab-grown human tissues to identify possible treatments
June 8, 2020 - Dr. William Stanford and his colleagues are using human tissue models to understand why COVID-19 makes some patients severely ill. |
COVID-19 research moving at ‘lightning speed’, thanks to generous community support
May 8, 2020 - Researchers at The Ottawa Hospital are working around the clock to advance more than 50 potentially life-saving research projects to support the world-wide effort to find better ways to treat and prevent COVID-19. Now, nine of these projects have ... |
Researchers use lab-grown human tissues to understand secrets of COVID-19 infection, identify possible treatments
April 29, 2020 - A team of Ontario researchers is using 3D lab-grown human tissue models to understand why COVID-19 makes some patients severely ill. They also hope to identify drugs that can reduce the severity of the infection. |
Harnessing stem cells and regenerative medicine to fight COVID-19
April 23, 2020 - Researchers from The Ottawa Hospital and the University of Ottawa have been awarded $490,000 from the Stem Cell Network for two research projects that could help in the fight against COVID-19. These peer-reviewed grants are part of an overall ... |
New method can help labs around the world grow stem cells more efficiently
January 15, 2020 - Researchers from Dr. William Stanford’s lab have developed a more efficient way to grow all kinds of cells from induced pluripotent stem cells (iPSCs). |
Precision medicine approach for leukemia awarded $1.5M
May 1, 2019 - Acute myeloid leukemia (AML) is one of the deadliest forms of cancer. A team of researchers from The Ottawa Hospital and uOttawa is hoping to revolutionize treatment for AML by developing a “precision medicine” approach. |
3D gel helps researchers find potential drugs for lung cancer, other diseases
March 15, 2019 - Researchers in Ottawa and Toronto have created a spongy 3D gel that mimics lung tissue, allowing them to quickly screen hundreds of potential drugs for lung cancer and other diseases. |
Dr. William Stanford has been named The Ottawa Hospital’s Chrétien Researcher of the Year for his work on blood cancer and other diseases
October 23, 2018 - When Dr. William Stanford first became a biological scientist, he simply followed his curiosity and was happy to let others pursue any practical applications of his research. Today, he goes on bedside rounds with clinicians, meets with patients ... |
New drug combination destroys chemo-resistant blood cancer
October 22, 2018 - Researchers from The Ottawa Hospital and the University of Ottawa have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia (AML) and a diagnostic test to determine which AML patients would most likely ... |
Top Research Papers from The Ottawa Hospital 2015-2017
June 7, 2018 - Did you know that researchers at The Ottawa Hospital publish an average of four new scientific papers every single day? Our research is advancing science and improving health on a massive scale – both at home and around the world. The list below ... |
How a rubber chicken helped create a novel model of a rare lung disease
December 12, 2017 - In 2009, Dr. William Stanford received a “laughter basket” including a rubber chicken from a young woman with a rare lung disease. Although he had never heard of her disease, called lymphangioleiomyomatosis (LAM), he was intrigued enough to meet wi |
Researchers turn back the clock to watch aging in fast forward
July 20, 2017 - Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disease that resembles rapid aging, with young children displaying hardened blood vessels, fragile bones and wrinkles among other symptoms. It usually results in death during the teenage |
Could stem cells heal premature lungs, fight infections, build muscles and strengthen bones?
May 25, 2017 - Ottawa researchers closer to finding out, thanks to $1.5 million from the Ontario Institute for Regenerative Medicine
Researchers from The Ottawa Hospital, CHEO and the University of Ottawa are bringing discoveries made in the lab closer to huma |
The Ottawa Hospital awarded 18 research grants from the Canadian Institutes of Health Research, worth $10.7 million
May 19, 2017 - Eighteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded nearly $11 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a suc |
A how-to-kit for cells: $250K grant to map how stem cells become muscle and cartilage
August 31, 2016 - Dr. William Stanford was awarded $250,000 from the Natural Sciences and Engineering Research Council of Canada to develop molecular maps of how stem cells become muscle and cartilage. A stem cell is influenced by a large collection of regulatory |
Stem cell therapy rejuvenates old, brittle bones in osteoporosis model
March 17, 2016 - Approximately a quarter of all Canadians will suffer a fracture because of weak bones (osteoporosis) in their lifetime, costing the health care system more than $2.3 billion each year1. Despite the huge burden of this disease, treatments for age- |
$1M grant to help researchers unravel the secrets behind super-powered leukemia cells
February 3, 2016 - Drs. William Stanford, Caryn Ito, Theodore Perkins and Mitchell Sabloff were awarded $1M from the Canadian Institutes of Health Research (CIHR) to learn more about a protein that’s missing from 40 percent of Acute Myeloid Leukemia (AML) ... |
Ottawa stroke researchers awarded nearly $500,000
June 17, 2015 - The HSF Canadian Partnership for Stroke Recovery has awarded nearly $500,000 for a number of stroke research projects in Ottawa. Dr. Paul Albert had the top-ranked grant in the competition (and won the Dr. Tony Hakim Stroke Research Award) for his pr |
$700,000 grant to advance use of stem cells to study rare disease
May 20, 2015 - Dr. Bill Stanford has been awarded more than US$700,000 over three years from the United States Congressionally Directed Medical Research Program to use stem cells to study the rare genetic disease Tuberous sclerosis and the related lung tumor Lymp |
