Dilworth Lab

Jeff Dilworth profile picture

Contact Information

Jeff Dilworth, PhD
613-737-8899 ext. 70339

ORCID logo https://orcid.org/0000-0002-6265-8102


Selected Publications

K. Nakka, S. Hachmer, Z. Mokhtari, R. Kovac, H. Bandukwala, C. Bernard, Y. Li, G. Xie, C. Liu, M. Fahalli, L. Megeney, J. Gondin, B. Chazaud, M. Brand, X. Zha, K. Ge, and F.J. Dilworth. JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment. Science 377: 666-669, 2022.

D. Robinson, M. Ritso, G. Nelson, Z. Mokhtari, K. Nakka, H. Bandukwala, S. Goldman, P. Park, R. Mounier, B. Chazaud, M. Brand, M. Rudnicki, K. Adelman, F.J. Dilworth. Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation. Dev Cell 56: 1014-1029, 2021.

M. Brand, K. Nakka, J. Zhu, and F.J. Dilworth. Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function. Cell Stem Cell 4: 518-533, 2019.

H. Faralli, C. Wang, A. Benyoucef, S. Sebastian, L. Zhuang, A. Chu, C. Palii, C. Liu, B. Camellato, M. Brand, K. Ge, and F.J. Dilworth. H3K27-demethylase activity of UTX/KDM6A is essential for skeletal muscle regeneration. Journal of Clinical Investigation 126: 1555-1565, 2016.

S. Sebastian, H. Faralli, Z. Yao, P. Rakopoulos, C. Palii, Y. Cao, K. Singh, Q-C. Liu, A. Chu, A. Aziz, M. Brand, S.J. Tapscott, and F.J. Dilworth. Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation. Genes & Dev 27: 1247-1259, 2013.

S. Rampalli, L. Li, E. Mak, K. Ge, M. Brand, S.J. Tapscott, and F.J. Dilworth. p38 MAPK signaling pathway regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nature Struct Mol Biol 14: 1150-1156, 2007.

PubMed Listings

For more publications use this PubMed ID link.