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Contact Information

Jonathan Angel, MD, FRCPC
(613) 737-8442

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Selected Publications

- A.M. Crawley, S. Faucher, J.B. Angel. “Soluble IL-7 Rα (CD127) inhibits IL-7 activity and is increased in HIV infection.” J Immunol 184:4679-4687, 2010.

- J.B. Angel, J.-P. Routy, C. Tremblay, D. Ayers, R. Woods, J. Singer, N. Bernard, C. Kovacs, F. Smaill, S. Gurunathan, R.-P. Sekaly. “A Randomized Controlled Trial of HIV Therapeutic Vaccination Using ALVAC With or Without Remune” AIDS 25:731-739, 2011.

- C.T. Costiniuk, D.A. Fergusson, S. Doucette, J.B. Angel. “Discontinuation of Pneumocystis jirovecii Pneumonia prophylaxis with CD4+ <200 cells/µL and virologic suppression: A systematic review.” PLoS One 6(12): e28570, 2011.

- A. Crawley, J.B. Angel. “The influence of HIV on CD127 expression and its potential implications of IL-7 therapy.” Seminars in Immunology 24(3): 231-240, 2012.

- C.T. Costiniuk, C. Kovacs, J.P. Routy, J. Singer, S. Gurunathan, R.P. Sekaly, J.B.Angel. “Human immunodeficiency virus rebound in blood and seminal plasma following discontinuation of antiretroviral therapy.” AIDS Res Hum Retroviruses 29(2): 266-269, 2013.

All Other Publications

- A. Vranjkovic, A.M. Crawley, K. Gee, A. Kumar, J.B. Angel. “IL-7 decreases IL-7 receptor-α (CD127) expression and induces shedding of CD127 by human CD8+ T cells.” Internat Immunol 19(12):1329-1339, 2007.

- J. B. Angel, W. Greaves, D. Ward, A. Rodriguez, D. Scevola, L. Nieto, E. De Jesus. “Virologic and Immunologic Activity of PEG Intron in HIV Disease” AIDS 23:2431-2438, 2009.

- A. Vranjkovic, A.M. Crawley, A. Patey, J.B. Angel. “IL-7-dependent STAT-5 activation and CD8+ T-cell proliferation are impaired in HIV infection” J Leukoc Biol 89 (4):499-506, 2011.

- C. Costiniuk, J.B. Angel. “Human Immunodeficiency Virus and the gastrointestinal immune system: Does Highly Active Antiretroviral Therapy Restore Gut Immunity?” Mucosal Immunol 5(6):596-604, 2012.

- A. M. Crawley, A. Vranjkovic, E. Faller, M. McGuinty, B. Aurelia, S. Burke, S. Cousineau, A. Kumar, P.A. MacPherson, J.B. Angel. “Jak/STAT and PI3K signalling pathways have both common and distinct roles in IL-7 mediated activities in human CD8+ T-cells” J. Leuk. Biol. 95(1):117-127, 2014.