Brian Hutton profile picture

Contact Information

Brian Hutton, MSc, PhD
613-737-8899 ext 73842
bhutton@ohri.ca



ORCID logo https://orcid.org/0000-0001-5662-8647

Publications

Selected Publications

Access to many of the listed publications can be sought from https://www.researchgate.net/profile/Brian_Hutton/publications.

Evaluating comparative effectiveness of psychosocial interventions adjunctive to opioid agonist therapy for opioid use disorder: A systematic review with network meta-analyses. Rice D, Corace K, Wolfe D, Esmaeilisaraji L, Michaud A, Grima A, Austin B, Douma R, Barbeau P, Butler C, Willows M, Poulin PA, Sproule BA, Porath A, Garber G, Taha S, Garner G, Skidmore B, Moher D, Thavorn K, Hutton B. PLoS One. 2020 Dec 28;15(12):e0244401. doi: 10.1371/journal.pone.0244401.

An Evaluation of Distiller SR's Machine Learning-based Prioritization Tool for Title/Abstract Screening–Impact on Reviewer-Relevant Outcomes. Hamel C, Kelly SE Thavorn K, Rice D, Wells G, Hutton B. BMC Medical Research Methodology. 2020 Oct 15;20(1):256.

Optimising weight-loss interventions in cancer patients – A systematic review and network meta-analysis. Levasseur N, Cheng W, Mazzarello S, Clemons M, Vandermeer L, Jones L, Joy A, Barbeau P, Wolfe D, Ahmadzai N, Hersi M, Stober C, Shorr R, Hilton J, Hutton B. PloS One 16(2): e0245794.

A systematic review and network meta-analysis of existing pharmacologic therapies in patients with idiopathic sudden sensorineural hearing loss. Ahmadzai N, Cheng W, Kilty S, Esmaeilisaraji L, Wolfe D, Bonaparte J, Schramm D, Fitzpatrick E, Lin V, Moher D, Hutton B. PLOS One 14(9): 2019.

The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials. Catalá-López F, Hutton B, Núñez-Beltrán A, Page MJ, Ridao M, Macías Saint-Gerons D, Catalá MA, Tabarés-Seisdedos R, Moher D. PLoS One. 2017 Jul 12;12(7):e0180355. doi: 10.1371/journal.pone.0180355. eCollection 2017.

The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. Ann Intern Med. 2015 Jun 2;162(11):777-84.

Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Quach P, Skidmore B, Moher D, Alvarez GG. BMC Infect Dis. 2017 Apr 11;17(1):265.

Network meta-analysis for comparing treatment effects of multiple interventions: an introduction. Catalá-López F, Tobías A, Cameron C, Moher D, Hutton B. Rheumatol International. 2014 Apr 2

The quality of reporting methods and results in network meta-analyses: an overview of reviews and suggestions for improvement. Hutton B, Salanti G, Chaimani A, Caldwell DM, Schmid C, Thorlund K, Mills E, Catalá-López F, Turner L, Altman DG, Moher D. PLoS One. 2014 Mar 26;9(3):e92508. doi: 10.1371/journal.pone.0092508. eCollection 2014.

All Other Publications

A Selection of Publications:

Kanji S, Morin S, Agtarap K, Purkayastha D, Thabet P, Bosse D, Wang X, Lunny C, Hutton B. Adverse Events Associated with Immune Checkpoint Inhibitors: Overview of Systematic Reviews. Drugs. 2022 May;82(7):793-809. doi: 10.1007/s40265-022-01707-1.

McIsaac DI, Gill M, Boland L, Hutton B, Branje K, Shaw J, Grudzinski AL, Barone N, Gillis C; Prehabilitation Knowledge Network. Prehabilitation in adult patients undergoing surgery: an umbrella review of systematic reviews. Br J Anaesth. 2022 Feb;128(2):244-257. doi: 10.1016/j.bja.2021.11.014. Epub 2021 Dec 16.

Cole KM, Clemons M, Alzahrani M, Liu M, Larocque G, MacDonald F, Hutton B, Piper A, Fernandes R, Pond GR, Vandermeer L, Emam KE, McGee SF. Vasomotor symptoms in early breast cancer-a "real world" exploration of the patient experience. Support Care Cancer. 2022 May;30(5):4437-4446. doi: 10.1007/s00520-022-06848-3.

Catalá -López F, Driver JA, Page MJ, Hutton B, Ridao M, Berrozpe-Villabona C, Alonso-Arroyo A, Fraga-Medín CA, Bernal-Delgado E, Valencia A, Tabarés-Seisdedos R. Design and methodological characteristics of studies using observational routinely collected health data for investigating the link between cancer and neurodegenerative diseases: protocol for a meta-research study. BMJ Open. 2022 Apr 29;12(4):e058738. doi: 10.1136/bmjopen-2021-058738.

Medrea I, Christie S, Tepper SJ, Thavorn K, Hutton B. Network meta-analysis of therapies for cluster headache: Effects of acute therapies for episodic and chronic cluster. Headache. 2022 Apr;62(4):482-511. doi: 10.1111/head.14283.

McGee S, Clemons M, Liu M, Alzahrani M, Ng T, Awan A, Sehdev S, Hilton J, Caudrelier JM, Savard MF, Fallowfield L, Kumar V, Freedman O, Fergusson D, Pond G, Hutton B, Bourque JM. A randomized, pragmatic trial investigating the timing of radiotherapy and endocrine in patients with early stage breast cancer (REaCT-RETT trial). Cancer Research (2022).

Catalá -López F, Hutton B, Page MJ, Driver JA, Ridao M, Alonso-Arroyo A, Valencia A, Macías Saint-Gerons D, Tabarés-Seisdedos R. Mortality in Persons With Autism Spectrum Disorder or Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis. JAMA Pediatr. 2022 Apr 1;176(4):e216401. doi: 10.1001/jamapediatrics.2021.6401.

Corace K, Suschinsky K, Wyman J, Leece P, Cragg S, Konefal S, Pana P, Barrass S, Porath A, Hutton B. Evaluating how has care been affected by the Ontario COVID-19 Opioid Agonist Treatment Guidance: Patients' and prescribers' experiences with changes in unsupervised dosing. Int J Drug Policy. 2022 Apr;102:103573. doi: 10.1016/j.drugpo.2021.103573.

Medrea I, Christie S, Tepper SJ, Thavorn K, Hutton B. Effects of acute and preventive therapies for episodic and chronic cluster headache: A scoping review of the literature. Headache. 2022 Mar;62(3):329-362. doi: 10.1111/head.14284.

Fakhraei R, Denize K, Simon A, Sharif A, Zhu-Pawlowsky J, Dingwall-Harvey ALJ, Hutton B, Pratt M, Skidmore B, Ahmadzai N, Heslehurst N, Hayes L, Flynn AC, Velez MP, Smith G, Lanes A, Rybak N, Walker M, Gaudet L. Predictors of Adverse Pregnancy Outcomes in Pregnant Women Living with Obesity: A Systematic Review. Int J Environ Res Public Health. 2022 Feb 12;19(4):2063. doi: 10.3390/ijerph19042063.

 Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: an overview of systematic reviews. Thabet P, Joshi A, MacDonald E, Cheng W, Stevens A, Hutton B, Kanji S. PloS One 16(1): e0244966.

A randomized trial of individualized versus standard of care antiemetic therapy for breast cancer patients at high risk for chemotherapy-induced nausea and vomiting. Clemons M, Dranitsaris G, Sienkiewicz M, Sehdev S, Ng T, Robinson A, Mates M, Hsu T, McGee S, Feedman O, Kumar V, Fergusson D, Hutton B, Vandermeer L, Hilton J. Breast. 2020 Nov 10;54:278-285.

Combination Tests in the Diagnosis of Chronic Periprosthetic Joint Infection: Systematic Review and Development of a Stepwise Clinical Decision-Making Tool. Abdelbary H, Cheng W, Ahmadzai N, Carli AV, Shea BJ, Hutton B, Fergusson D, Beaulé P. J Bone Joint Surg Am. 2020 Nov 4; 102(21S Suppl 1):114-124.

A randomized trial comparing vascular access strategies for patients receiving chemotherapy with trastuzumab for early stage breast cancer. Clemons M, Stober C, Kehoe A, Bedard A, McDonald F, Brunet MC, Saunders D, Vandermeer L, Mazzarello S, Awan A, Basulaiman B, Robinson A, Mallick R, Hutton B, Fergusson D. Supportive Care in Cancer. 2020 Oct;28(10):4891-4899.

Rapid review methods more challenging during COVID-19: commentary with a focus on 8 knowledge synthesis steps. Tricco AC, Garritty CM, Boulos L, Lockwood C, Wilson M, McGowan J, McCaul M, Hutton B, Clement F, Mittmann N, Devane D, Langlois EV, Abou-Setta AM, Houghton C, Glenton C, Kelly SE, Welch VA, LeBlanc A, Wells GA, Pham B, Lewin S, Straus SE. J Clin Epidemiol. 2020 Oct;126:177-183.

Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses. Hutton B, Hersi M, Cheng W, Pratt M, Barbeau P, Mazzarello S, Ahmadzai N, Skidmore B, Morgan SC, Bordeleau L, Ginex PK, Sadeghirad B, Morgan RL, Cole KM, Clemons M. Oncology Nursing Forum. 2020 Jul 1;47(4):E86-E106.

Canadian guideline for Parkinson disease.Grimes D, Fitzpatrick M, Gordon J, Miyasaki J, Fon E, Schlossmocher M, Suchowersky O, Rajput A, Lafontaine AL, Mestre T, Appel-Cresswell S, Kalia S, Schoffer K, Zurowski M, Postuma R, Udow S, Fox S, Barbeau P, Hutton B. CMAJ 191(36): E989-E1004; 2019.

A question of trust: can we build an evidence base to gain trust in systematic review automation technologies? O'Connor A, Tsafnat G, Thomas J, Glasziou P, Gilbert S, Hutton B. Systematic Reviews 8(1): 2019.

Guselkumab for the treatment of moderate-to-severe plaque psoriasis during induction phase: a systematic review and network meta-analysis. Cameron C, Druchok C, Hutton B, McElligott S, Nair S, Schubert A, Situ A, Varu A, Villacorta R. Journal of Psoriasis and Psoriatic Arthritis 4(2); 81-92: 2019.

Evaluating Comparative Effectiveness of Psychosocial Interventions for Persons Receiving Opioid Agonist Therapy for Opioid Use Disorder: Protocol for a Systematic Review. Hutton B, Rice D, Poulin P, Sproule B, Wolfe D, Moher D, Thavorn K, Garber G, Taha S, Porath A, Willows M, Esmaelisaraji L, Yazdi F, Shea B, Skidmore B, Corace K. BMJ Open (2018).

Incidence, causes, and consequences of preventable adverse drug reactions occurring in inpatients: A systematic review of systematic reviews. Wolfe D, Yazdi F, Kanji S, Burry L, Beck A, Butler C, Esmaeilisaraji L, Hamel C, Hersi M, Skidmore B, Moher D, Hutton B. PloS One (2018); 13(10).

Comparative safety of bowel cleansers: protocol for a systematic review and network meta-analysis. Barbeau P, Wolfe, Yazdi F, Rice D, Dube C, Rostom A, Kanji S, Skidmore B, Moher D, Hutton B. BMJ Open (2018); 8 (6). 

A systematic review of adverse events of rifapentine and isoniazid compared to other treatments for latent tuberculosis infection. Hutton B, Pease C, Yazdi F, Wolfe D, Hamel C, Barbeau P, Skidmore B, Alvarez G. Pharmacoepidemiology and Drug Safety (2018); 27 (6): 557-566. 

Guselkumab for the treatment of moderate-to-severe plaque psoriasis during induction phase: a systematic review and network meta-analysis. Cameron C, Druchok C, Hutton B, McElligott S, Nair S, Schubert A, Situ A, Varu A, Villacorta R. Journal of Psoriasis and Psoriatic Arthritis (2018).

Herceptin®(trastuzumab) in HER2-positive early breast cancer: a systematic review and cumulative network meta-analysis. Wilson F, Coombes M, Brezden-Masley C, Yurchenko M, Wylie Q, Douma R, Varu A, Hutton B, Skidmore B, Cameron C. Systematic Reviews (2018); 7(1). 

The importance of assessing and adjusting for cross-study heterogeneity in network meta-analysis: a case study assessing the comparative efficacy of treatments for moderate-to-severe psoriasis. Cameron C, Hutton B, Druchok C, McElligott S, Nair S, Schubert A, Situ A, Varu A, Villacorta R. Journal of Comparative Effectiveness Research (2018).

Optimal vascular access strategies for patients receiving chemotherapy for early-stage breast cancer: a systematic review. Robinson A, Souied O, Bota B, Levasseur N, Stober C, Hilton J, Kamel D, Hutton B, Vandermeer L, Mazzarello S, Joy A, Fergusson D, McDiarmid S, McInnes M, Shorr R, Clemons M. Breast Cancer Research and Treatment (2018); 171(3).

Reporting guidance considerations from a statistical perspective: overview of tools to enhance the rigour of reporting of randomised trials and systematic reviews. Hutton B, Wolfe D, Moher D, Shamseer L. Evid Based Ment Health. 2017 May;20(2):46-52.

The Importance of Considering Differences in Study Design in Network Meta-analysis: An Application Using Anti-Tumor Necrosis Factor Drugs for Ulcerative Colitis. Cameron C, Ewara E, Wilson FR, Varu A, Dyrda P, Hutton B, Ingham M. Med Decis Making. 2017 Nov;37(8):894-904.

Defining optimal control of chemotherapy-induced nausea and vomiting-based on patients' experience. Hernandez Torres C, Mazzarello S, Ng T, Dranitsaris G, Hutton B, Smith S, Munro A, Jacobs C, Clemons M. Support Care Cancer. 2015 Jun 25.

Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis. Tricco AC, Soobiah C, Blondal E, Veroniki AA, Khan PA, Vafaei A, Ivory J, Strifler L, Ashoor H, MacDonald H, Reynen E, Robson R, Ho J, Ng C, Antony J, Mrklas K, Hutton B, Hemmelgarn BR, Moher D, Straus SE. BMC Med. 2015 Jun 1813:142.

Comparative efficacy of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis. Tricco AC, Soobiah C, Blondal E, Veroniki AA, Khan PA, Vafaei A, Ivory J, Strifler L, Ashoor H, MacDonald H, Reynen E, Robson R, Ho J, Ng C, Antony J, Mrklas K, Hutton B, Hemmelgarn BR, Moher D, Straus SE. BMC Med. 2015 Jun 18;13:136.

A Microsoft-Excel-based tool for running and critically appraising network meta-analysesan overview and application of NetMetaXL. Brown S, Hutton B, Clifford T, Coyle D, Grima D, Wells G, Cameron C. Syst Rev. 2014 Sep 29;3:110.

Management of urogenital atrophy in breast cancer patients: a systematic review of available evidence from randomized trials. Mazzarello S, Hutton B, Ibrahim MF, Jacobs C, Shorr R, Smith S, Ng T, Clemons M. Breast Cancer Res Treat. 2015 Jul;152(1):1-8.

Stop this waste of people, animals and money. Moher D, Shamseer L, Cobey KD, Lalu MM, Galipeau J, Avey MT, Ahmadzai N, Alabousi M, Barbeau P, Beck A, Daniel R, Frank R, Ghannad M, Hamel C, Hersi M, Hutton B, Isupov I, McGrath TA, McInnes MDF, Page MJ, Pratt M, Pussegoda K, Shea B, Srivastava A, Stevens A, Thavorn K, van Katwyk S, Ward R, Wolfe D, Yazdi F, Yu AM, Ziai H. Nature. 2017 Sep 6;549(7670):23-25.

Chemotherapy-Induced Nausea and Vomiting: Time for More Emphasis on Nausea? Ng TL, Hutton B, Clemons M. Oncologist. 2015 Jun;20(6):576-83.

Treatment choices for patients with invasive lobular breast cancer: a doctor survey.
Jacobs C, Ibrahim MF, Clemons M, Hutton B, Simos D, Caudrelier JM, Graham ID, Smith S, Addison C, Arnaout A. J Eval Clin Pract. 2015 Aug;21(4):740-8.

The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: protocol for a systematic review and network meta-analysis of randomized controlled trials. Catalá-López F, Hutton B, Núñez-Beltrán A, Mayhew AD, Page MJ, Ridao M, Tobías A, Catalá MA, Tabarés-Seisdedos R, Moher D. Syst Rev. 2015 Feb 27;4:19.

Is there a role for oral or intravenous ascorbate (vitamin C) in treating patients with cancer? A systematic review. Jacobs C, Hutton B, Ng T, Shorr R, Clemons M. Oncologist. 2015 Feb;20(2):210-23.

Network meta-analysis for comparing treatment effects of multiple interventions: an introduction. Catalá-López F, Tobías A, Cameron C, Moher D, Hutton B. Rheumatol Int. 2014 Nov;34(11):1489-96.

Safety, effectiveness, and cost effectiveness of long acting versus intermediate acting insulin for patients with type 1 diabetes: systematic review and network meta-analysis. Tricco AC, Ashoor HM, Antony J, Beyene J, Veroniki AA, Isaranuwatchai W, Harrington A, Wilson C, Tsouros S, Soobiah C, Yu CH, Hutton B, Hoch JS, Hemmelgarn BR, Moher D, Majumdar SR, Straus SE. BMJ. 2014 Oct 1;349:g5459.

Comparison of physical interventions, behavioral interventions, natural health products, and pharmacologics to manage hot flashes in patients with breast or prostate cancer: protocol for a systematic review incorporating network meta-analyses. Hutton B, Yazdi F, Bordeleau L, Morgan S, Cameron C, Kanji S, Fergusson D, Tricco A, Straus S, Skidmore B, Hersi M, Pratt M, Mazzarello S, Brouwers M, Moher D, Clemons M. Syst Rev. 2015 Aug 27;4(1):114

The incidence of post-intubation hypotension associated with emergent intubations performed outside of the operating room: a systematic review. Green R, Hutton B, Lorette J, Fergusson D. Canadian Journal of Emergency Medicine 2014.

Effect of fresh red blood cell transfusions on clinical outcomes in premature, very low-birth-weight infants: the ARIPI randomized trial. Fergusson DA, Hébert P, Hogan DL, LeBel L, Rouvinez-Bouali N, Smyth JA, Sankaran K, Tinmouth, A Blajchman MA, Kovacs L, Lachance C, Lee S, Walker CR, Hutton B, Ducharme R, Balchin K, Ramsay T, Ford JC, Kakadekar A, Ramesh K, Shapiro S. JAMA, 2012 October 10; 308(14):1443-51.

The effect of English language restriction on systematic review based meta-analyses: a systematic review of empirical studies. Morrison A, Polisena J, Husereau D, Moulton K, Clark M, Fiander M, Mierzwinski-Urbain M, Clifford T, Hutton B, Rabb D. International Journal of Technology Assessment in Healthcare, 2012 April 28(2); 138-44.

Home telehealth for chronic obstructive pulmonary disease: a systematic review and meta-analysis. Polisena J, Tran K, Cimon K, Hutton B, McGill S, Palmer K, Scott RE. J Telemed Telecare. 2010; 16(3):120-7.

Home telemonitoring for congestive heart failure: a systematic review and meta-analysis. Polisena J, Tran K, Cimon K, Hutton B, McGill S, Palmer K, Scott RE. J Telemed Telecare. 2010; 16(2):68-76.

Home telehealth for diabetes management: a systematic review and meta-analysis. Polisena J, Tran K, Cimon K, Hutton B, McGill S, Palmer K. Diabetes Obes Metab. 2009 Oct; 11(10):913-30.

Effects of home-based pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S; Chronic Obstructive Pulmonary Disease Axis of Respiratory Health Network. Ann Intern Med. 2008 Dec 16; 149(12): 869-78.

Does analysis using “last observation carried forward” introduce bias in dementia research? Molnar FJ, Hutton B, Fergusson DA. CMAJ 2008; 179(8):751-3.

Have last-observation-carried-forward analyses caused us to favour more toxic dementia therapies over less toxic . Molnar FJ, Man-Son-Hing M, Hutton B, Fergusson DA. Open Medicine (March 2009).

Cooper C, Hutton B, Fergusson D, Mills E, Klein MB, Boivin G, Halperin S. A review of influenza vaccine immunogenicity and efficacy in HIV-infected adults. Can J Infect Dis Med Microbiol. 2008 Nov; 19(6):419-23.

Resuscutating patients with early severe sepsis: a Canadian multicentre observational study. McIntyre L, Fergusson D, Cook DJ, Nair RC, Bell D, Dhingra V, Hutton B, Magder S, Hebert PC. Canadian Journal of Anesthesia October 2007; 54(10): 790-98.

Prophylactic vaccination against human papillomavirus (HPV) in women: a systematic review of randomized controlled trials. Rambout L, Hopkins L, Fung Kee Fung M, Hutton B, Shorr R, Fergusson D. Canadian Medical Association Journal 2007 Aug 28; 177(5): 469-479.

A 15-year analysis of early and late autologous hematopoietic stem cell transplant in relapsed, aggressive, transformed, and nontransformed follicular lymphoma. Sabloff M, Atkins HL, Bence-Bruckler I, Bredeson C, Fergusson D, Genest P, Hopkins H, Hutton B, Mcdiarmid S, Huebsch LB. Biology of Blood and Marrow Transplantation 2007; 13: 956-964.

Meta-analysis: intravenous immunoglobulin in critically ill adult patients withsepsis. Turgeon AF, Hutton B, Fergusson DA, McIntyre L, Tinmouth AA, Cameron DW, Hebert PC. Ann Intern Med. 2007 Feb 6; 146(3):193-203.

The Epidemiology of Major Joint Contractures: A Systematic Review of the Literature. Fergusson D, Hutton B, Drodge A. Clin Orthop Relat Res. 2006 Dec 14.

Use of intravenous immunoglobulin for treatment of recurrent miscarriage: a systematic review. Hutton B, Sharma R, Fergusson D, Tinmouth A, Hebert P, Jamieson J, Walker M. BJOG. 2007 Feb; 114(2):134-42.

Reliability of point-of-care testing for glucose measurement in critically ill adults. Kanji S, Buffie J, Hutton B, Bunting PS, Singh A, McDonald K, Fergusson D, McIntyre LA, Hebert PC. Crit Care Med. 2005 Dec; 33(12):2778-85.

Randomized controlled trials of aprotinin in cardiac surgery: could clinical equipoise have stopped the bleeding? Fergusson D, Glass KC, Hutton B, Shapiro S. Clin Trials. 2005;2(3):218-29

Association between suicide attempts and selective serotonin reuptake inhibitors: systematic review of randomized trials. Fergusson D, Doucette S, Glass KC, Shapiro S, Healy D, Hebert P, Hutton B. BMJ (2005); 330 (7488): 396.

Changes in body weight and serum lipid profile in obese patients treated with orlistat in addition to a hypocaloric diet: a systematic review of randomized clinical trials. Hutton B, Fergusson DA. American Journal of Clinical Nutrition (2004) ;80(6): 1461-8.

PubMed Listings

For more publications use this PubMed ID link.