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Contact Information

Guy Trudel, MD
613-737-8899 ext. 75591

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Guy Trudel

Clinician Investigator, Inflammation & Chronic Disease
Ottawa Hospital Research Institute
Professor of Medcine, Surgery and Biochemistry
University of Ottawa
Bone and Joint Research Laboratory
The Ottawa Hospital Rehabilitation Centre
MARROW Space Research
International Space Station Payload

Research Interests

  • Musculoskeletal effects of immobility
  • Joint contractures
  • Tendinopathies
  • Gene expression in the capsule and cartilage in contractures
  • Pannus proliferation in contractures, histomorphometric and biological study
  • Hematopoiesis with immobility

Brief Biography

Dr. Guy Trudel runs a clinical practice and research program in Ottawa Canada. His tertiary academic rehabilitation unit delivers rehabilitation care to people after polytrauma and serious / complex medical and surgical complications.

For the past 20 years, as Director of the Bone and Joint Research Laboratory, Dr Trudel has pursued clinical and laboratory-based research on 3 areas related to the musculoskeletal complications of immobility: joint contractures, tendonopathies and fat accumulation in the bone marrow. Dr. Trudel’s Ottawa University internationally collaborative team has published over 60 original papers during his tenure, with studies supported by CIHR, Canadian, European and German Space Agencies.

Selected Publications

Guy Trudel, Gerd Melkus, Greg O. Cron, Hakim Louati, Adnan Sheikh, Peder E.Z. Larson, Mark Schweitzer, Peter Lapner, Hans K. Uhthoff, Odette Laneuville.  Ultra-high field imaging of the rabbit supraspinatus enthesis: a 4-week time course after repair surgery and effect of channeling. Journal of Magnetic Resonance Imaging. 2017.

Campbell Mark, Laneuville Odette, Guy Trudel.  Knee flexion contractures in patients with osteoarthritis: clinical features and histologic characterization of the posterior capsule.  PM&R 12;466-73, 2015.

Mehdi Kordi, Daniel L. Belavý, Gabriele Armbrecht, Adnan Sheikh, Dieter Felsenberg, Guy Trudel.  Loss and re-adaptation of lumbar intervertebral disc water signal intensity after prolonged bedrest. Journal of Musculoskeletal and Neuronal Interactions. 15, 294-300; 2015.

Guy Trudel, Odette Laneuville Elizabeth Coletta, Louis Goudreau, Hans K. Uhthoff.  Quantitative and Temporal Differential Recovery of Articular and Muscular Limitations of Knee Joint Contractures; Results in a Rat Model. Journal of Applied Physiology. 177(7), 730-737, 2014.

Guy Trudel
, Elisabeth Coletta, Ian Cameron, Daniel L. Belavý, Martin Lecompte, Gabriele Armbrecht, Dieter Felsenberg, Hans Uhthoff.  Resistive exercises with or without whole-body vibration prevent vertebral marrow fat accumulation during 60 days of head-down tilt bed rest in men. Journal of Applied Physiology. 112:1824-1831, 2012. 

Diseases, conditions and populations of interest

Research and clinical approaches