Dylan Burger profile picture

Contact Information

Dylan Burger, PhD
613-562-5800 x 8241
dburger@uottawa.ca

2513-451 Smyth Rd.
Ottawa, ON
K1H 7N9



ORCID logo https://orcid.org/0000-0003-3951-2911

Research Activities

1. Ongoing Research Projects 

Microparticles in diabetes (CIHR, CFI, ORF)
This project explores the impact of diabetes on extracellular vesicle formation and signaling. We believe that large extracellular vesicles (microparticles) are both markers and mediators of vascular injury in diabetes.

Relevant Publication(s)

https://www.ncbi.nlm.nih.gov/pubmed/28601907
https://pubmed.ncbi.nlm.nih.gov/25514595/

Assessing the impact of renal replacement on extracellular vesicles
(KFoC, Co-PI with Dr. Marcel Ruzicka)
In collaboration with Dr. Marcel Ruzicka we are studying the impact of renal replacement on microparticles. We have focused our studies in two areas: 1) peritoneal dialysis where we provided the first evidence that the solutions used for peritoneal dialysis cause stress to the peritoneum resulting in microparticle formation. and 2) The impact of hemodialysis on extracellular vesicles

Relevant Publication(s)
https://www.ncbi.nlm.nih.gov/pubmed/28540060
https://pubmed.ncbi.nlm.nih.gov/31375072/

Urinary microparticles in renal disease (Diabetes Canada, CFI, ORF)
We have a longstanding interest in understanding the role of urinary large extracellular vesicles (microparticles) as markers and mediators of kidney disease. We have focused attention on animal and human diabetes and, more recently, on childhood nephrotic syndrome in collaboration with Dr. Janusz Feber- CHEO)

Relevant Publication(s)

https://www.ncbi.nlm.nih.gov/pubmed/28004150
https://pubmed.ncbi.nlm.nih.gov/33037887/
https://pubmed.ncbi.nlm.nih.gov/31990489/
https://pubmed.ncbi.nlm.nih.gov/29435202/
https://pubmed.ncbi.nlm.nih.gov/28004150/
https://pubmed.ncbi.nlm.nih.gov/24676640/

2. Other Research Interests

a. Therapeutic potential of vascular progenitor-derived exosomes
b. Defining the basic physical properties of extracellular vesicles
c. Novel techniques for submicron particle assessment
d. Role of extracellular vesicles in aging