Cognitive Health in Multiple Sclerosis Research Lab

Lisa Walker profile picture

Contact Information

Lisa Walker, PhD, C.Psych
613-737-8894
lwalker@ottawahospital.on.ca

Fax -613-737-8895



ORCID logo https://orcid.org/0000-0001-5865-7257

What We Do

Our lab studies cognitive health in individuals with multiple sclerosis.  We have an active grant-funded research program that evaluates various aspects of cognition in this population.  We have a particular interest in the following areas:
- cognitive fatigability
- the impact of stem-cell therapies on cognition
- the relationship between cognition and various biomarkers of disease (e.g. imaging, sNfL)
- the assessment of cognition (e.g. psychometrics)
- the impact of exercise interventions on cognition

Our lab consists of a number of dedicated health professionals who are passionate about what we do.  It is our collective goal to improve the quality of life in those people with MS whom we serve.

Selected Publications

Walker, L.A.S., Lindsay-Brown, A.P. & Berard, J.A. (2019). Cognitive fatigability interventions in neurological conditions: A systematic review. Neurology and Therapy, 8(2), 251-271. (published on-line 4 October 2019). http://link.springer.com/article/10.1007/s40120-019-00158-3. PMID: 31586303

Walker, L.A.S., Gardner, C., Freedman, M.S., MacLean, H., Rush, C. & Bowman, M. (2019). Research-to-practice gaps in multiple sclerosis care in one Canadian centre for those with subjective cognitive, mental health and psychosocial concerns. International Journal of MS Care, 21, 243-248. (published on-line Dec. 4, 2018). https://doi.org/10.7224/1537-2073.2017-090. PMID: 31889928

Walker, L.A.S., Marino, D., Berard, J.A., Feinstein, A., Morrow, S.A., Cousineau, D. (2017). Canadian normative data for Minimal Assessment of Cognitive Function in Multiple Sclerosis. Canadian Journal of Neurological Sciences, 44, 547-555 (first published on-line Jul 7, 2017). https://doi.org/10.1017/cjn.2017.199 PMID: 28683843 (Corrigendum – Canadian Journal of Neurological Sciences, 45(5), 604. https://doi.org/10.1017/cjn.2018.308)

Berard, J.A., Fang, Z., Walker, L.A.S., Lindsay-Brown, A., Osman, L., Cameron, I., Cruce, R., Cron, G.O., Freedman, M.S. & Smith, A.M. (2019). Imaging cognitive fatigue in multiple sclerosis: Objective quantification of cerebral blood flow during a task of sustained attention using ASL perfusion fMRI. Brain Imaging and Behavior. (published on-line 29 August 2019). doi: 10.1007/s11682-019-00192-7. PMID: 31468375.

Atkins, H.L., Bowman, M., Allan, D., Anstee, G., Arnold, D.L., Bar-Or, A., Bence-Bruckler, I., Birch, P., Bredeson, C., Chen, J., Fergusson, D., Halpenny, M., Hamelin, L., Heubsch, L., Hutton, B., Laneuville, P., Lapierre, Y., Lee, H., Martin, L., McDiarmid, S., O’Connor, P., Ramsay, T., Sabloff, M., Walker, L.A.S. & Freedman, M.S. (2016; 6-12 Aug). Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial. The Lancet, 388 (10044), 576-585, (online 9 June 2016) http://dx.doi.org/10.1016/S0140-6736(16)30169-6 PMID: 27291994

Meet the Cognitive Health in Multiple Sclerosis Lab