Success stories: research breakthroughs thanks to StemCore

StemCore is proud to have played a role in many key discoveries at The Ottawa Hospital and the University of Ottawa. Selected success stories are profiled below.

Hyaluronic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle
August 4, 2022 - A new study published in the journal Science reveals a unique form of cell communication that controls muscle repair.
Lab-grown “mini-kidneys” unlock secrets of a rare disease
July 21, 2022 - Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumours in patients with tuberous sclerosis complex (TSC).
MicroRNA protects mice from acute kidney injury
October 6, 2021 - New research led by Dr. Kevin Burns shows that intravenous delivery of a type of microRNA can protect mice from acute kidney injury, a serious and untreatable condition.
50 ways to repair an ovary? Study suggests multiple pathways can create stem-like ovarian cells
August 17, 2021 - Approximately every 28 days, hundreds of cells die and disintegrate on the ovary’s surface as an egg breaks through and begins its journey. Ovaries have become masters at repairing this damage, but exactly how they do this remains a mystery.
Research unravels links between fasting, lifespan and muscle stem cells
June 2, 2021 - Intermittent fasting (or skipping meals) has often been reported to increase lifespan in various animals, but the observation that it also affects muscle stem cell function has been less well-studied.
Stem cells go ‘all in’ to repair damaged muscles
May 12, 2021 - When faced with a major muscle injury, muscle stem cells need to find the right balance between repair and self-preservation. New research led by Dr. Jeff Dilworth shows for the first time that upon injury, muscle stem cells prioritize immediate repa
Studying sex differences in kidney disease could open door to developing new treatments
January 27, 2021 - During critical illnesses like septic shock, the kidneys are often the first to shut down and the last to recover, if they recover at all. Previous research has shown that men are more severely affected by this kind of acute kidney injury than women,
Using lab-grown human tissues to identify possible treatments
June 8, 2020 - Dr. William Stanford and his colleagues are using human tissue models to understand why COVID-19 makes some patients severely ill.
COVID-19 research moving at ‘lightning speed’, thanks to generous community support
May 8, 2020 - Researchers at The Ottawa Hospital are working around the clock to advance more than 50 potentially life-saving research projects to support the world-wide effort to find better ways to treat and prevent COVID-19. Now, nine of these projects have bee
Researchers and research staff honoured for outstanding work in cancer clinical trials, emergency medicine, cell sorting and tissue collection
April 29, 2020 - A number of outstanding researchers and research teams have been honoured through The Ottawa Hospital’s Excellence Awards program for 2020. They include the Rethinking Clinical Trials (REaCT) program, Senior Clinical Research Associate in Emergency M

2019

10/22/2019 12:00:00 AM - How does a stem cell know what to be when it grows up?
10/9/2019 12:00:00 AM - “Wild idea” opens possible new frontier for preventing ovarian cancer
10/2/2019 12:00:00 AM - Researchers reveal the circuitry regulating muscle stem cell function
9/25/2019 12:00:00 AM - Unravelling the mystery of how one gene contributes to Parkinson’s, Crohn’s and leprosy
5/17/2019 12:00:00 AM - $950,000 to help develop stem cell treatments for septic shock, lung injury and muscle degeneration
5/1/2019 12:00:00 AM - Precision medicine approach for leukemia awarded $1.5M
1/31/2019 12:00:00 AM - Discovery points to innovative new way to treat Duchenne muscular dystrophy

2018

10/22/2018 12:00:00 AM - New drug combination destroys chemo-resistant blood cancer
9/10/2018 12:00:00 AM - Often-overlooked Natural Killer cells may be key to cancer immunotherapy
9/6/2018 12:00:00 AM - How does type 1 diabetes start? New research implicates early metabolic defects in the pancreas
7/20/2018 12:00:00 AM - $1.7 million to advance research on colon cancer, brain development, kidney disease and severe fluid loss
7/11/2018 12:00:00 AM - Estrogen and ovarian cancer: study provides first molecular link
7/11/2018 12:00:00 AM - Researchers uncover possible new mechanism to enhance cancer-killing viruses

2016

10/11/2016 12:00:00 AM - $2-million project aims to bring personalized medicine to lung cancer care