StemCore is proud to have played a role in many key discoveries at The Ottawa Hospital
and the University of Ottawa. Selected success stories are profiled below.
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Engineered lung tissue model reveals possible new treatment for lymphangioleiomyomatosis
July 12, 2023
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A research team led by Dr. Bill Stanford has discovered a new class of drugs that may be effective in treating lymphangioleiomyomatosis (LAM). This rare disease is characterized by abnormal cell growth in the lungs which can lead to severe breathing
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Novel stem cell drives ‘remarkable’ regeneration of tiny blood vessels in the lung
May 15, 2023
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Dr. Duncan Stewart’s team has identified a novel stem cell with a remarkable ability to regenerate and repair the tiny blood vessels in the lungs.
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Prenatal exposure to low doses of methylmercury causes autism-like behaviors in mice
March 9, 2023
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A study co-led by Dr. Jing Wang and Dr. Laurie Chan is the first to show that exposing pregnant mice to low doses of methylmercury causes autism-like behaviors in their offspring.
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Study could lead to new treatments for pulmonary hypertension and right heart failure
February 28, 2023
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The human heart has a remarkable ability to adapt and compensate in the face of injury and disease, but unfortunately this isn’t universal.
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Tweaking the ovary’s immune system may help prevent ovarian cancer
October 5, 2022
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The diabetes drug metformin prevents fibrosis in the ovaries by adjusting the organ’s immune cells, according to a study in mice published in Science Advances.
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Research reveals novel mechanism controlling muscle stem cells
October 5, 2022
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New research from Dr. Michael Rudnicki’s team shows for the first time that a cellular structure called a primary cilium, which functions somewhat like an antenna, plays a crucial role in priming muscle stem cells for repair and regeneration.
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Hyaluronic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle
August 4, 2022
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A new study published in the journal Science reveals a unique form of cell communication that controls muscle repair.
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Lab-grown “mini-kidneys” unlock secrets of a rare disease
July 21, 2022
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Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumours in patients with tuberous sclerosis complex (TSC).
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MicroRNA protects mice from acute kidney injury
October 6, 2021
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New research led by Dr. Kevin Burns shows that intravenous delivery of a type of microRNA can protect mice from acute kidney injury, a serious and untreatable condition.
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50 ways to repair an ovary? Study suggests multiple pathways can create stem-like ovarian cells
August 17, 2021
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Approximately every 28 days, hundreds of cells die and disintegrate on the ovary’s surface as an egg breaks through and begins its journey. Ovaries have become masters at repairing this damage, but exactly how they do this remains a mystery.
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