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Cancer + past stroke increases stroke risk nearly 3-fold
January 29, 2024
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A study co-led by Drs Deborah Siegal and Rinku Sutradhar found that people who had a stroke prior to a cancer diagnosis were nearly three times more likely to have a future stroke compared to other cancer patients.
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Experts call for tighter standards to speed emergency treatment of intracerebral hemorrhage
January 26, 2024
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Most experts agree that “time is brain” when it comes to treating stroke, but this principle hasn’t always been applied evenly to different kinds of stroke.
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The Ottawa Hospital uses breakthrough stroke technology to improve patient care
January 24, 2024
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Using the world’s smallest camera, physicians can see inside blood vessels during patient procedures for the first time
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Global research trial for ICH stroke a major step forward for patients
October 25, 2023
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Dr. Dar Dowlatshahi is leading the Canadian site of the research trial and hopes it will change the way we treat the deadliest and least treatable form of stroke.
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Sci-fi developments and rock ’n’ roll
October 25, 2023
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Meet Dr. Dar Dowlatshahi, stroke researcher and literal rock star at The Ottawa Hospital
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CT scan results help predict which mini-strokes lead to major strokes
June 8, 2023
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This is the first study to confirm the additional risk of stroke related to these findings. It also suggests that adding these CT findings to TIA decision tools would further improve physicians’ ability to predict a patient’s future stroke risk and p
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How a heart attack drug is revolutionizing stroke treatment
May 11, 2023
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A clot-busting drug developed to treat heart attack is now being used as a standard treatment for acute ischemic stroke, thanks in large part to research at The Ottawa Hospital.
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Molecule triggered by running could help with stroke recovery
April 18, 2023
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Research suggests that VGF plays a key role in healing the brain after stroke
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ELEVATE seed grants to help researchers at The Ottawa Hospital develop better treatments and improve patient care
February 1, 2023
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The Ottawa Hospital’s Research Institute is awarding five ELEVATE seed grants to early-career researchers to spur the development of innovative treatments and better patient care.
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Life-altering stroke treatment and care from a “gym rat”
January 26, 2023
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Meet Dr. Robert Fahed, one of only four interventional neurologists in Canada
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Neurologist blazes new trails in stroke research
November 2, 2022
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For a neurology resident who spent the last five years sleeping in hospitals and saving lives, Dr. Ronda Lun’s research accomplishments are nothing short of incredible.
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Breakthrough could revolutionize stroke treatment
June 29, 2022
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In the largest stroke clinical trial ever run in Canada, researchers have shown Tenecteplase (TNK), a safe, well tolerated drug, commonly used as a clot buster for heart attacks, is an effective treatment for acute ischemic stroke, a stroke caused by
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Researchers at The Ottawa Hospital awarded five grants for high risk, high reward and interdisciplinary research
April 4, 2022
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The New Frontiers in Research Fund (NFRF) 2021 Exploration competition has awarded $25 million to support 102 research teams across Canada that bring diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
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Study reinforces new treatment option for stroke prevention
February 17, 2022
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A network meta-analysis led by Dr. Dar Dowlatshahi and neurology resident Dr. Ronda Lun found that ticagrelor is just as good as clopidogrel when combined with aspirin as a dual antiplatelet therapy.
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Getting the clot out on first try improves outcomes for basilar artery stroke patients
January 21, 2022
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Pulling a clot out of the brain on the first try significantly improves outcomes for patients with basilar artery stroke, according to a study published in Stroke led by Dr. Robert Fahed. This rare kind stroke can cause death or severe disability by
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Researchers at The Ottawa Hospital awarded three grants for high risk, high reward and interdisciplinary research
May 31, 2021
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The New Frontiers in Research Fund (NFRF) 2020 Exploration competition brings diverse disciplines together in pursuit of breakthrough ideas and high-reward outcomes.
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Tool predicts which mini-strokes could lead to major strokes
February 3, 2021
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A made-in-Ottawa tool can help emergency physicians predict which patients with mini-strokes are at greatest risk of having a major stroke within the week, according to a study published in The BMJ.
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Can a diabetes drug help repair damaged nerve insulation? Mouse study shows it might.
January 27, 2021
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A study in mice led by Dr. Jing Wang suggests that the diabetes drug metformin may be able to repair damage to nerve insulation caused by diseases like MS and stroke.
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New scientist profile: Dr. Robert Fahed wants more people to benefit from life-saving stroke therapy
May 27, 2020
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Dr. Robert Fahed saves lives by pulling blood clots out of the brains of stroke patients. This minimally invasive procedure called thrombectomy has revolutionized stroke care, and Dr. Fahed wants as many patients as possible to benefit. However, he’s
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Updated Ottawa Rules app could help doctors predict strokes, catch deadly brain bleeds
May 14, 2020
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A free app for emergency department physicians based on Ottawa’s world-renowned clinical decision rules has added more rules to its roster.
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Researchers awarded $1.6M to improve care for cardiovascular disease
November 13, 2019
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The Heart and Stroke Foundation of Canada has awarded $1.6M to researchers at The Ottawa Hospital, affiliated with the University of Ottawa.
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How a lucky accident helped spark a new era of depression research
October 21, 2019
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It all started with one lucky accident. In the late 1980’s, Dr. Paul Albert was trying to isolate a gene that controls metabolism. Instead, he pulled out a gene that controls motivation and another that controls mood. These two genes became the subje
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Feature grant: Researchers investigate how cholesterol regulates inflammation in white blood cells
August 7, 2019
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Drs. Xiaohui Zha and Alexander Sorisky were awarded $48,000 to test whether cholesterol regulates inflammation in human white blood cells by altering gene expression.
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The Ottawa Hospital awarded 13 grants worth $11.2 million from Canadian Institutes of Health Research
July 26, 2019
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Researchers at The Ottawa Hospital have been awarded 13 grants worth a total of $11.2 million from the Canadian Institutes of Health Research (CIHR). The new projects focus on areas such as cancer immunotherapy, hepatitis C infection, blood clots, ar
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Provincial innovation award for a computer tablet that could help stroke patients recover
January 9, 2019
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Dr. Dar Dowlatshahi has been honored with the 2018 e-Health, Technology, and Monitoring Excellence Award by the Innovation Fund Provincial Oversight Committee. His team’s project “Recover Now: Mobile Tablet-based Stroke Rehabilitation in the Acute Ca
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Study shows which stroke patients benefit most from clot-busting drug
October 25, 2018
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Dr. Dar Dowlatshahi co-authored an international study that could help predict which ischemic stroke patients would benefit the most from a clot-busting drug. This kind of stroke can be treated with the drug alteplase or by running a long thin tube t
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Research project aims to get stroke survivors moving
October 24, 2018
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Exercise has been proven to enhance brain repair, decrease depression, maintain cognitive function and reduce frailty in stroke survivors. However, stroke survivors don’t always have access to evidence-based exercise programs in the community. A new
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Researchers awarded $1.7 M to tackle stroke and heart attack from multiple angles
October 2, 2018
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Five groups from The Ottawa Hospital, affiliated with the University of Ottawa, were successful in the Heart and Stroke Foundation's recent grant competition. Drs. Dar Dowlatshahi, Tim Ramsay and Elizabeth Rochon were awarded $290,000* to test whethe
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Could leaky blood vessels be a target for treating migraines? Study opens up promising new area of research
August 30, 2018
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Migraine headaches are often accompanied by electrical waves that slowly move across the brain, causing flashes of light and other visual disturbances. Referred to as “migraine aura”, this phenomenon also affects the brain’s blood vessels, allowing
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Diabetes drug could enhance stem cell treatment for stroke
August 8, 2018
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Imagine removing blood or skin cells from a patient after a stroke, turning them into powerful stem cells in the lab, and then transplanting them back into the same patient's brain so they can give rise to new neurons to repair the damage. This is th
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Can a calculator predict your risk of heart attack and stroke?
July 23, 2018
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Canadian researchers have built and validated an online calculator that empowers individuals to predict their risk of cardiovascular disease. Their process was published today in the journal CMAJ, and the calculator is available at projectbiglife.com
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Researchers and support staff recognized at The Ottawa Hospital’s Excellence Awards ceremony
May 25, 2018
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Several inspiring research staff were honoured at The Ottawa Hospital’s Excellence Awards ceremony on May 22. The Ottawa Stroke Program received the Research Excellence Team Award and Amy Geertsma received the Inspire Award for Outstanding Clinical R
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Could a skin cancer drug help treat stroke?
April 18, 2018
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Dr. Hsiao-Huei Chen and her team discovered that a drug used to treat skin cancer reduced brain damage after stroke in animal models. While a lack of blood flow that supplies oxygen and nutrients is the first thing to kill brain cells after a strok
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Could stem cells repair the heart, fight infections, mend premature lungs, and heal the brain after stroke?
April 11, 2018
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Ottawa researchers closer to finding out, thanks to $999,900 from the Stem Cell Network
Researchers from The Ottawa Hospital, CHEO and the University of Ottawa are bringing discoveries made in the lab closer to human trials and therapies, thanks
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Antidepressants and exercise in stroke recovery: surprising results from new mouse study
March 2, 2018
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Exercise and selective serotonin reuptake inhibitors (SSRIs) are effective in treating certain kinds of depression, but little research has tested them together in post-stroke depression, which affects 20 to 80 percent of stroke survivors. Drs. Pau
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The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate
January 30, 2018
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Sixteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $12.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a success r
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Pre-treated cells boost blood vessel repair
November 29, 2017
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Endothelial colony-forming cells (ECFCs) are stem-like cells found in umbilical cord blood that help repair damaged blood vessels. They may hold promise for the treatment of stroke, heart attack and blocked leg arteries. However, their rate of bloo
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Researchers get $558K boost from Heart and Stroke Foundation
June 15, 2017
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Two scientists from The Ottawa Hospital and the University of Ottawa were successful in the Heart and Stroke Foundation’s recent grant-in-aid grant competition. Dr. Baptiste Lacoste was awarded $259,000* to test whether drugs that are already used
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New model may lead to better treatments for depression after stroke
September 14, 2016
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Dr. Paul Albert and his team have developed a new animal model to help test treatments for depression after stroke. Between 20 to 80 percent of stroke patients will be diagnosed with depression, which greatly impacts both their quality of life an
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Could an algorithm help treat bleeding strokes?
March 2, 2016
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Intracerebral hemorrhages, or bleeding strokes, kill approximately 500 people in Ontario each year. One in three victims are still bleeding when they arrive at the hospital and could potentially be helped by experimental drugs that promote blood
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Silent strokes more common than thought; and a major cause of dementia
July 9, 2014
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Dr. Antoine Hakim has published a perspective piece in the prestigious journal Nature concerning “covert” or “silent” strokes that occur in people without producing the usual signs and symptoms of an overt stroke. As part of a special edition of Natu
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