Brian Hutton profile picture

Contact Information

Brian Hutton, MSc, PhD
613-737-8899 ext 73842

Brian Hutton

Senior Scientist, Clinical Epidemiology Program
Ottawa Hospital Research Institute
Director, Knowledge Synthesis Unit
Ottawa Hospital Research Institute
Assistant Professor, School of Epidemiology, Public Health and Preventive Medicine
University of Ottawa

Research Interests

Systematic reviews and meta-analysis; network meta-analysis; technology assessment; statistical methods; oncology; mental health and addiction.

Brief Biography

Dr. Hutton is a Senior Scientist with the OHRI's Clinical Epidemiology Program, Director of the Knowledge Synthesis Unit and an Assistant Professor within the University of Ottawa's Faculty of Epidemiology and Community Medicine. His primary research interests currently lie in the realm of network meta-analysis, systematic reviews and other forms of evidence synthesis. He is a leader in the OHRI's CIHR-funded knowledge synthesis group which conducts network meta-analysis research projects and other forms of knowledge synthesis for the Drug Safety and Effectiveness Network, with current and past topics including treatments for latent tuberculosis, the influence of industry relationships on prescribing, and the incidence of preventable adverse drug reactions. Dr. Hutton was awarded a 5-year CIHR New Investigator Award and led the development of the extension of the PRISMA statement for reporting of network meta-analyses. Dr. Hutton also contributes time to the Ottawa Hospital Methods Center and Ottawa Regional Cancer Center in the roles of methodologist and biostatistician. His past and current research includes works in the realms of oncology, transfusion medicine, infectious diseases, mental health and several other clinical fields. Most recently Dr. Hutton has undertaken research related the evaluation of interventions for opioid use disorder and the health effects of cannabis consumption.

Selected Publications

Access to many of the listed publications can be sought from

The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials. Catalá-López F, Hutton B, Núñez-Beltrán A, Page MJ, Ridao M, Macías Saint-Gerons D, Catalá MA, Tabarés-Seisdedos R, Moher D. PLoS One. 2017 Jul 12;12(7):e0180355. doi: 10.1371/journal.pone.0180355. eCollection 2017.

 The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catalá-López F, Gøtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D. Ann Intern Med. 2015 Jun 2;162(11):777-84.

Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses. Pease C, Hutton B, Yazdi F, Wolfe D, Hamel C, Quach P, Skidmore B, Moher D, Alvarez GG. BMC Infect Dis. 2017 Apr 11;17(1):265.

Network meta-analysis for comparing treatment effects of multiple interventions: an introduction. Catalá-López F, Tobías A, Cameron C, Moher D, Hutton B. Rheumatol International. 2014 Apr 2

The quality of reporting methods and results in network meta-analyses: an overview of reviews and suggestions for improvement. Hutton B, Salanti G, Chaimani A, Caldwell DM, Schmid C, Thorlund K, Mills E, Catalá-López F, Turner L, Altman DG, Moher D. PLoS One. 2014 Mar 26;9(3):e92508. doi: 10.1371/journal.pone.0092508. eCollection 2014.

Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies. Hutton B, Joseph L, Fergusson D, Mazer CD, Shapiro S, Tinmouth A. BMJ. 2012 Sep 11;345:e5798. doi: 10.1136/bmj.e5798.

Should de-escalation of bone-targeting agents be standard of care for patients with bone metastases from breast cancer? A systematic review and meta-analysis. Ibrahim MF, Mazzarello S, Shorr R, Vandermeer L, Jacobs C, Hilton J, Hutton B, Clemons M. Ann Oncol. 2015 Jun 28.

Diseases, conditions and populations of interest

Addiction; Anxiety; Breast cancer; Cancer; Depression

Research and clinical approaches

Biostatistics; Clinical research; Clinical trials; Cohort studies; Epidemiology; Health research methods; Patient safety; Public health; Rapid reviews; Systematic reviews