Research News

	Canadian researchers awarded international prize for COVID-19 Evidence Network March 3, 2022 - Dr. Jeremy Grimshaw and Dr. John Lavis recently accepted the international REWARD prize from Cochrane on behalf of the COVID-19 Evidence Network (COVID-END) for their efforts to get reliable and timely COVID-19 evidence summaries to decision makers,
	Study reinforces new treatment option for stroke prevention February 17, 2022 - A network meta-analysis led by Dr. Dar Dowlatshahi and neurology resident Dr. Ronda Lun found that ticagrelor is just as good as clopidogrel when combined with aspirin as a dual antiplatelet therapy.
	Tiny particles hold promise for treating acute and chronic lung disease February 17, 2022 - A meta-analysis of lab studies found that tiny particles called extracellular vesicles (EVs) released by mesenchymal stem/stromal cells (MSCs) have clear potential for treating acute lung injury,
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	Scientists call for "living evidence reviews" to combat COVID confusion December 15, 2021 - Policy missteps will continue to overshadow the global response to Covid because policymakers are overwhelmed with rapidly shifting research evidence, according to scientists writing in the peer-reviewed journal Nature.
	Researchers update guidance on colorectal cancer screening in patients with IBDs November 4, 2021 - Dr. Sanjay Murthy was the lead author in a Clinical Practice Update (CPU) for the American Gastroenterological Association on how to prevent, detect and manage colorectal neoplastic lesions in patients with inflammatory bowel diseases (IBDs) based on
	Study establishes bleeding risk with long-term use of blood thinners for life-threatening clots October 20, 2021 - A new systematic review and meta-analysis now provides the best data yet on the long-term risks and consequences of bleeding with different blood thinners.
	Is there a link between suicide and epidemics? August 1, 2021 - A systematic review published by Dr. Simon Hatcher, in partnership with researchers across Ontario, the United Kingdom, and Ireland, looked at the relationship between public health epidemics and the risk of suicide and self-harm.
	Researchers update PRISMA guideline to improve health research March 29, 2021 - Dr. David Moher and colleagues have published an updated PRISMA 2020 statement and explanation and elaboration to ensure these important guidelines continue to help researchers produce high-quality systematic reviews.
	New scientist profile: Dr. Darine El-Chaâr aims to help pregnant parents and their babies March 10, 2021 - Dr. Darine El-Chaâr’s research focuses on three areas: increasing breast/chestfeeding among patients with diabetes, cannabis use in pregnancy, and COVID-19 in pregnancy.
	New scientist profile: Dr. Jess Fiedorowicz brings an interdisciplinary vision to mental health research March 10, 2021 - Dr. Jess Fiedorowicz has built his research career on bringing together specialists from different disciplines to better understand the health risks faced by people with severe mental disorders, with a focus on bipolar disorder.
	Can chest imaging diagnose COVID-19? December 9, 2020 - An international team led by Dr. Matthew McInnes is regularly combing the latest research to find out whether chest imaging could be a useful tool for diagnosing COVID-19.
	Jeremy Grimshaw, David Moher and Peter Tugwell ranked among world’s top researchers November 24, 2020 - Three senior scientists at The Ottawa Hospital, affiliated with uOttawa, have been ranked among the top researchers in the world for 2020.
	Blueprint Excelerator helps move discoveries from the bench to the bedside November 6, 2020 - The Blueprint Translational Research Group was established in 2016 at The Ottawa Hospital, in collaboration with the Ottawa Methods Centre. Co-led by Dr. Dean Fergusson and Dr. Manoj Lalu, Blueprint developed an innovative model called the Excelerato
	Dr. Peter Tugwell wins Barer-Flood Prize in Health Services and Policy Research September 30, 2020 - The prize recognizes a senior researcher in the field of health services and policy research who has made a significant impact on policy research, policy and/or care delivery in Canada.
	Dr. David Moher elected a Fellow of the Royal Society of Canada September 16, 2020 - One of the world’s most cited researchers, Dr. Moher is considered a pioneer in the science of conducting and reporting systematic reviews, and has dedicated his career to supporting the global academic community in reporting clinical research.
	COVID-19 Evidence Network to support decision-making May 11, 2020 - To help leaders around the world respond to unprecedented challenges related to COVID-19, Drs. Jeremy Grimshaw and John Lavis are co-leading The COVID-19 Evidence Network to support Decision-making (COVID-END). Partners in the network include experts
	How likely are you to survive in-hospital cardiac arrest? Newly identified risk factors can help with difficult decisions December 4, 2019 - A paper published in the BMJ is the first to identify risk factors that affect patient survival after in-hospital cardiac arrest. This new information can help patients, families and care providers decide on their care goals upon admission to hospita
	aSAH survivor and her daughter help advance stroke research October 23, 2019 - When 61-year-old Debi Borbridge had an aSAH, a rare form of stroke, little did she know that two years later she and her daughter would be helping to shape the future of research in this field.
	Milestone study will help doctors treat life threatening blood clots October 22, 2019 - Faizan Khan’s research will influence how doctors around the world treat venous thrombosis, the third-deadliest cardiovascular disease. This is a remarkable achievement for a PhD candidate in the early stages of his career.
	Dr. Susan Rogers Van Katwyk honoured for research on how countries fight antimicrobial resistance October 22, 2019 - Recent PhD graduate, Dr. Susan Rogers Van Katwyk will receive an honourable mention for the Worton Researcher in Training Award for her impressive research on strategies to fight antimicrobial resistance.
	Ottawa-led team stands out for patient decision aids research October 8, 2019 - Dr. Dawn Stacey has earned the distinction of having her Cochrane systematic review cited more than any other Cochrane Review published in 2018.
	The promise of CAR-T therapy for cancer: meta-analysis shows the big picture August 14, 2019 - CAR-T therapy, which uses a patient’s own genetically modified immune cells, is one of the most exciting advances in cancer treatment. To get a big picture view of the field, Drs. Manoj Lalu and Dean Fergusson led a team that analyzed data from nearl
	Study establishes long-term risks and consequences of leg vein clot recurrence July 31, 2019 - Over 750,000 Canadians will have an unexplained vein blood clot in their lifetime, known as venous thrombosis. A collaborative study led by Dr. Marc Rodger and Faizan Khan now provides the best data yet on the long-term risks and consequences of recu
	Study updates sleep parameters for men and women in different age groups May 1, 2019 - Researchers hope new age and sex-based sleep parameters will improve the interpretation of sleep studies and the diagnosis of sleep disorders. They may also help reduce the unnecessary use of sleeping pills by older adults.
	Dr. Dawn Stacey one of Canada’s top nurse academics March 29, 2019 - Dr. Dawn Stacey has been ranked as one of the most cited nurse academics in Canada. According to a paper published in the Journal of Advanced Nursing, Dr. Stacey’s research has been cited 7241 times in the Scopus database over her career, putting her
	Jeremy Grimshaw and David Moher ranked among world’s top researchers March 8, 2019 - Drs. Jeremy Grimshaw and David Moher have once again been ranked among the world’s top scientists. According to Clarivate Analytics, they are both among the most highly cited scientists in the world in the field of Social Sciences, with tens of thous
	Preventing blood clots from coming back March 1, 2019 - Dr. Marc Carrier and his colleagues pooled data from more than 22,000 patients around the world to compare the effectiveness of multiple blood thinners to treat venous thromboembolism.
	New scientist profile: Dr. Swapnil Hiremath harnesses science to bust medical myths January 29, 2019 - Dr. Swapnil Hiremath is inspired by his patients to uncover the truth behind medical dogma. For example, he played a lead role in busting the myth that contrast dye should never be used in medical imaging in people with serious kidney disease. He is
	Chance encounter on a train led to an award-winning career in research October 22, 2018 - A job on the Rocky Mountaineer train took Dr. Kristin Danko to places that weren’t on the route between Vancouver and Calgary. One stop was a research lab at The Ottawa Hospital. Now she is the recipient of the Worton Researcher in Training Award fro
	Researchers awarded $1.7 M to tackle stroke and heart attack from multiple angles October 2, 2018 - Five groups from The Ottawa Hospital, affiliated with the University of Ottawa, were successful in the Heart and Stroke Foundation's recent grant competition. Drs. Dar Dowlatshahi, Tim Ramsay and Elizabeth Rochon were awarded $290,000* to test whethe
	The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate January 30, 2018 - Sixteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $12.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a success r
	Finding better ways to bring health research to life: World-leading Centre for Implementation Research opens at The Ottawa Hospital January 18, 2018 - Researchers regularly make discoveries that have the potential to improve patient care and quality of life. However, getting those findings adopted by health-care systems can be a challenge. Researchers at The Ottawa Hospital are already world l
	Top journal recognizes Ottawa expertise in patient decision aids August 17, 2017 - Dr. Dawn Stacey and her colleagues were invited by the prestigious Journal of the American Medical Association (JAMA) to submit a summary of their recent Cochrane systematic review on patient decision aids. The review reports on the effectiveness
	Ottawa researchers develop rapid review process to help WHO respond to global threats December 22, 2016 - Ms. Chantelle Garritty and collaborators in the Knowledge Synthesis Group have developed a process to help the World Health Organization (WHO) quickly create guidelines during global emergencies. During an outbreak of a new disease, WHO needs to a
	Ottawa research informs international Ebola guideline June 14, 2016 - Should clinicians wear double gloves or single gloves when caring for Ebola patients? What about full gowns versus coveralls? After Ebola broke out in West Africa in late 2013, the World Health Organization (WHO) asked Dr. David Moher and his tea

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Allan, David MD FRCPC	Associate Scientist (Clinical Epidemiology)	Blood cancer, Vascular, heart and metabolic disease	Cell therapy, Regenerative medicine, Stem cells, Systematic reviews, Transfusions, Translational research, Transplantation
Black, Amanda MD, MPH, FRCSC	Associate Scientist (Clinical Epidemiology)	Pregnancy, Women's health	Clinical trials, Cohort studies, Health promotion, Surveys, Systematic reviews
Boet, Sylvain MD, PhD	Scientist (Clinical Epidemiology)	COVID-19	Anesthesiology, Behaviour, Clinical trials, Knowledge translation and implementation research, Patient engagement, Psychology, Qualitative methods, Quality Improvement, Surgery, Systematic reviews, Translational research
Breau, Rodney MD	Scientist (Clinical Epidemiology)	Cancer, Kidney disease, Prostate cancer	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Imaging, Patient decision aids, Patient engagement, Quality Improvement, Surgery, Systematic reviews, Transfusions
Castellucci, Lana MD, FRCPC, MSc	Scientist (Clinical Epidemiology)	Thrombosis / thromboembolism	Clinical research, Clinical trials, Cohort studies, Critical care, Patient engagement, Systematic reviews, Transfusions
Chen, Innie MD, MPH, FRCSC	Scientist (Clinical Epidemiology)	Health equity, Population health, Pregnancy, Women's health	Clinical research, Epidemiology, Health research methods, Patient engagement, Quality Improvement, Systematic reviews
Dennis, Kristopher MD FRCPC PhD	Clinician Investigator (Cancer Therapeutics)	Cancer, Colorectal cancer, First Nations, Inuit and Métis Health, Gastric cancer, Liver cancer, Pain, Pancreatic cancer	Behaviour, Biomarkers, Clinical research, Clinical trials, Cohort studies, Health professional behaviour change, Health services research, Palliative care, Pragmatic trials, Qualitative methods, Quality Improvement, Systematic reviews
El-Chaar, Darine MD, FRCSC, Msc	Associate Scientist (Clinical Epidemiology)	COVID-19, Diabetes, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
Fergusson, Dean PhD, MHA, FCAHS	Program Director and Senior Scientist (Clinical Epidemiology)	Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease	Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Grimshaw, Jeremy MBCHB, PHD	Senior Scientist (Clinical Epidemiology)	COVID-19	Behaviour, Cluster randomized trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Qualitative methods, Quality Improvement, Surveys, Systematic reviews
Hiremath, Swapnil MD, MPH, FASN	Associate Scientist (Clinical Epidemiology)	Chronic disease, Diabetes, Health in older peoples, Heart disease, Hypertension, Kidney disease, Population health, Vascular, heart and metabolic disease	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health services research, Imaging, Pharmacology, Pragmatic trials, Public health, Quality Improvement, Systematic reviews
Hutton, Brian MSc, PhD	Senior Scientist (Clinical Epidemiology)	Addiction, Anxiety, Breast cancer, Depression, Health equity, Health in disadvantaged peoples, Maternal and fetal health, Mental health, Population health, Suicide, Cancer	Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Patient safety, Public health, Rapid reviews, Biostatistics, Clinical trials, Systematic reviews
Kendzerska, Tetyana MD, PhD	Associate Scientist (Clinical Epidemiology)	Aging, Chronic disease, Chronic obstructive pulmonary disease, Heart disease, Lung disease, Population health, Women's health	Biostatistics, Clinical research, Cohort studies, Epidemiology, Health research methods, Health services research, Systematic reviews
Kwok, Edmund MD MHA MSc FRCPC	Clinician Investigator (Clinical Epidemiology)		Clinical research, Critical care, Emergency medicine, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Patient safety, Pragmatic trials, Qualitative methods, Quality Improvement, Rapid reviews, Systematic reviews
Lavallee, Luke MDCM, MSc, FRCSC	Associate Scientist (Clinical Epidemiology)	Cancer, Kidney disease, Population health, Prostate cancer	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health professional behaviour change, Imaging, Knowledge translation and implementation research, Patient decision aids, Quality Improvement, Surgery, Systematic reviews
Martel, Guillaume MD, MSc (Epi), FRCSC, FACS	Scientist (Clinical Epidemiology)	Anemia, Bleeding disorders, Colorectal cancer, Liver cancer, Liver disease, Pancreatic cancer	Anesthesiology, Clinical research, Clinical trials, Peri-operative medicine, Surgery, Systematic reviews, Transfusions
McInnes, Matthew MD PhD FRCPC	Scientist (Clinical Epidemiology)	Bladder cancer, Cancer, Prostate cancer	Clinical research, Epidemiology, Health research methods, Imaging, Journalology, Systematic reviews
McIsaac, Daniel MD, MPH, FRCPC	Scientist (Clinical Epidemiology)	Aging, Frailty, Health in older peoples, Pain, Population health	Anesthesiology, Artificial intelligence and data science, Big data, Biostatistics, Clinical research, Clinical trials, Cohort studies, Digital and mobile health, Epidemiology, Health services research, Patient engagement, Peri-operative medicine, Public health, Quality Improvement, Risk assessment, Surgery, Systematic reviews
Moher, David PhD	Senior Scientist (Clinical Epidemiology)		Journalology, Knowledge translation and implementation research, Patient engagement, Quality Improvement, Rapid reviews, Systematic reviews
Moore, Gregory MD, FRCPC	Clinician Investigator (Clinical Epidemiology)	Newborn and child health	Clinical research, Knowledge translation and implementation research, Patient decision aids, Qualitative methods, Quality Improvement, Shared decision making, Systematic reviews
Morgan, Scott MD, MSc, FRCPC	Clinician Investigator (Cancer Therapeutics)	Bladder cancer, Breast cancer, Cancer, Prostate cancer	Biomarkers, Clinical research, Clinical trials, Cohort studies, Imaging, Systematic reviews
Poulin, Patricia C. Psych.	Associate Scientist (Clinical Epidemiology)	Addiction, Anxiety, Cancer, Chronic pain, Depression, Health equity, Musculoskeletal conditions, Pain	Anesthesiology, Behaviour, Biomarkers, Clinical research, Clinical trials, Emergency medicine, Epidemiology, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Palliative care, Patient decision aids, Patient safety, Peri-operative medicine, Pragmatic trials, Psychology, Qualitative methods, Quality Improvement, Systematic reviews
Ramsay, Timothy PhD	Senior Scientist (Clinical Epidemiology)	Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, Dystonia, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury	Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Rodger, Marc MD	Affiliate Investigator (Clinical Epidemiology)	Pregnancy, Thrombosis / thromboembolism, Women's health	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Systematic reviews
Santos, Marlise MD (FRCPC), MSc, MPH	Clinician Investigator (Clinical Epidemiology)	Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Chronic disease, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease	Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Schramm, David MD SM FRCSC FACS	Associate Scientist (Clinical Epidemiology)	Cochlear implantation, Hearing loss	Biostatistics, Clinical research, Clinical trials, Epidemiology, Neuro-stimulation, Patient safety, Quality Improvement, Surgery, Systematic reviews
Solmi, Marco MD, PhD, Psychiatrist	Clinician Investigator (Clinical Epidemiology)	Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews
Stacey, Dawn RN, PhD, CON(C)	Senior Scientist (Clinical Epidemiology)		Clinical research, Clinical trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient decision aids, Patient engagement, Qualitative methods, Quality Improvement, Shared decision making, Surveys, Systematic reviews
Thavorn, Kednapa BPharm, MPharm, PhD	Senior Scientist (Clinical Epidemiology)	Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision	Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Tugwell, Peter O.C., MD, FRCPC	Senior Scientist (Clinical Epidemiology)	Arthritis, Chronic disease, Global health, Population health	Clinical research, Epidemiology, Knowledge translation and implementation research, Patient engagement, Public health, Systematic reviews
Vaillancourt, Christian MD, MSc, FRCPC, CSPQ	Senior Scientist (Clinical Epidemiology)	Cardiac arrest, Heart disease, Population health, Spinal cord injury, Traumatic brain injury, Traumatic injuries	Clinical decision rules, Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Critical care, Emergency medicine, Epidemiology, Health economics, Health professional behaviour change, Health services research, Knowledge translation and implementation research, Public health, Quality Improvement, Surveys, Systematic reviews
Walker, Mark MD, FRCPC, MSc, MScHCM	Senior Scientist (Clinical Epidemiology)	Global health, Health equity, Infertility, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health	Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health research methods, Health services research, Knowledge translation and implementation research, Pragmatic trials, Prevention, Public health, Quality Improvement, Rapid reviews, Risk assessment, Surveys, Systematic reviews
Walker, Lisa PhD, C.Psych	Clinician Investigator (Neuroscience)	Anxiety, Autoimmune disease, Autoimmune diseases of the nervous system, Brain and neuromuscular disease, Dementia, Depression, Mental health, Multiple sclerosis	Behaviour, Biomarkers, Clinical research, Exercise, Imaging, Psychology, Psychometrics, Rehabilitation, Stem cells, Systematic reviews, Translational research

Related Resources

Knowledge Synthesis Group at the Ottawa Hospital Research Institute