Bipolar

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of bipolar disorder and develop better treatments. This page includes selected news stories about our research on bipolar disorder, links to researchers working in this area and related resources. Learn more below.

Research News


The Ottawa Hospital joins landmark bipolar disorder research network BD2 The Ottawa Hospital joins landmark bipolar disorder research network BD2
July 8, 2025 - The Ottawa Hospital’s Research Institute has been awarded US$ 2.3 million to join Breakthrough Discoveries for thriving with Bipolar Disorder (BD²).
New scientist profile: Dr. Dargél is dedicated to enhancing early detection and care in bipolar disorder New scientist profile: Dr. Dargél is dedicated to enhancing early detection and care in bipolar disorder
May 28, 2024 - "My research aims to fundamentally improve the lives of those at risk of or living with bipolar disorder, especially youth and their families."
A conversation with Dr. Jess Fiedorowicz A conversation with Dr. Jess Fiedorowicz
August 18, 2021 - Dr. Jess Fiedorowicz is shining a light on mental health through his work and research at The Ottawa Hospital. Originally from the U.S., Dr. Fiedorowicz has been at our hospital since 2020 as the Head and Chief of the Department of Mental Health.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Dargel, Aroldo
M.D., Ph.D.
Associate Scientist
(Neuroscience)
Anxiety, Bipolar, Dementia, Depression, Diabetes, Hypertension, Mental health, Obesity, Population health, Suicide, Vascular, heart and metabolic disease Artificial intelligence and data science, Behaviour, Big data, Biomarkers, Biostatistics, Clinical research, Clinical trials, Digital and mobile health, Epidemiology, Health technology, Prevention, Psychology, Quality Improvement, Rapid reviews, Systematic reviews, Translational research
Fiedorowicz, Jess
MD, PhD
Scientist
(Neuroscience)
Bipolar, Mental health, Suicide, Vascular, heart and metabolic disease Clinical research, Epidemiology, Translational research
Ramsay, Timothy
PhD
Senior Scientist
(Methodological and Implementation Research)
Addiction, Alzheimer's, Amyotrophic lateral sclerosis, Anxiety, Ataxia, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Brain and neuromuscular disease, Chronic obstructive pulmonary disease, Colorectal cancer, Concussion, Cystic fibrosis, Dementia, Depression, First Nations, Inuit and Métis Health, HIV, Immigrant and refugee health, Influenza, Kidney disease, Lung cancer, Macular degeneration, Men's health, Multiple sclerosis, Muscular dystrophy, Myasthenia gravis, Obesity, Ovarian cancer, Parkinson's, Pulmonary hypertension, Septic shock, Spinal cord injury Artificial intelligence and data science, Behaviour, Biomaterials, Biostatistics, Cell therapy, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Drug development, Emergency medicine, Epidemiology, Health professional behaviour change, Health promotion, Health research methods, Health services research, Health technology, Immunization, Immunotherapy, Palliative care, Patient decision aids, Pharmacology, Pharmacy, Prevention, Psychology, Psychometrics, Public health, Qualitative methods, Quality Improvement, Regenerative medicine, Rehabilitation, Risk assessment, Shared decision making, Surgery, Surveys, Systematic reviews, Transfusions, Translational research, Transplantation, Viral therapy
Solmi, Marco
MD, PhD, Psychiatrist
Clinician Investigator
(Neuroscience)
Addiction, Anxiety, Attention deficit hyperactivity disorder (ADHD), Autism, Bipolar, Dementia, Depression, Mental health, Schizophrenia, Suicide Clinical research, Clinical trials, Cluster randomized trials, Cohort studies, Epidemiology, Health research methods, Neuro-stimulation, Pharmacology, Pragmatic trials, Surveys, Systematic reviews


Related Resources

Mental health research at The Ottawa Hospital

Search for clinical trials at The Ottawa Hospital related to this disease or condition.





Publications

The following research publications are pulled from PubMed using the search terms "Bipolar" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study.
2025-12-01

The semi-structured interview for bipolar at-risk states (SIBARS): psychometric properties and validation.
2025-10-15

Switch to mania after acute antidepressant treatment for bipolar depression: a systematic review and network meta-analysis of randomised controlled trials.
2025-09-01

Treatment approaches and efficacy in psychedelic-induced psychosis: A systematic review.
2025-08-01

Atlas of Gray Matter Volume Differences Across Psychiatric Conditions: A Systematic Review With a Novel Meta-Analysis That Considers Co-Occurring Disorders.
2025-07-01

SNP-associated differential methylation in ARHGEF38: insights into genetic-epigenetic interactions.
2025-06-01

Predicting 10-year risk of chronic kidney disease in lithium-treated patients with bipolar disorder: A risk model development and internal cross-validation study.
2025-06-01

Atypical depression and emotion dysregulation: Clinical and psychopathological features.
2025-05-01

Perspectives on Precision Psychiatry Using Antipsychotics in the Management of Bipolar Disorder.
2025-04-23

Psilocybin Dispensaries and Online Health Claims in Canada.
2025-04-01

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