Ottawa Hospital Research Institute

Research News

	Hormone therapy after prostate cancer surgery improves survival for some patients November 27, 2024 - “These results suggest that some patients should be offered hormone therapy after surgery based on how likely it is that their cancer will spread."
	Earlier use of bone-strengthening agents could benefit people with prostate cancer September 20, 2024 - “These bone-strengthening agents can decrease fracture rates and the need for radiation. We hope that this study will lead to earlier, more pro-active adoption.”
	Researchers at The Ottawa Hospital awarded 14 CIHR grants worth more than $10 million July 18, 2024 - “Success at CIHR underscores the creativity, dedication and collaboration of our researchers and their teams. Funding for these innovative projects paves the way for groundbreaking advancement in biomedical sciences, improved patient care and progres
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	New research reveals how immunotherapy drugs and viruses can work together to kill cancer cells July 5, 2024 - “These results will help guide ongoing efforts to combine checkpoint inhibitors with cancer-killing viruses in clinical trials."
	New scientist profile: Dr. Nicola Schieda aims to improve imaging diagnosis of prostate, kidney cancers October 5, 2022 - Radiologist Dr. Nicola Schieda works on algorithms to improve the non-invasive diagnosis of kidney and prostate cancers using MRI and CT scans.
	Researchers at The Ottawa Hospital awarded 18 CIHR grants worth more than $11 million February 5, 2022 - These projects will advance science and improve health in areas such as tuberculosis, blood disease, prostate cancer, heart disease, muscle repair, sleep apnea, brain cancer, medical imaging, virtual care, prehab, intellectual disability, sarcoma, CA
	Bone-modulating drugs can be given less often during cancer treatment, reducing side-effects and saving time and money November 28, 2020 - When cancer spreads to the bones, it can cause pain, reduce mobility and increase the risk of fractures. Bone modulating drugs can help, but a new study suggests that to maximize the value of these drugs, it may be better to give them less often.
	Prostate cancer study means more flexible treatment options for patients January 23, 2020 - A clinical trial led by Dr. Shawn Malone found that prostate cancer patients given hormone therapy prior to radiation therapy had similar outcomes compared with patients in whom both therapies were started simultaneously.
	Dr. Dawn Stacey co-hosts International Shared Decision Making Conference August 14, 2019 - Dr. Dawn Stacey co-hosted the International Shared Decision Making Conference in Quebec City with Dr. France Légaré. More than 400 people from 22 countries participated in the conference, which focused on Patient-Oriented Shared Decision Ma
	Clinicians at The Ottawa Hospital launch 14 innovative projects to improve health-care delivery, thanks to funding from TOHAMO and The Ottawa Hospital’s Research Institute March 22, 2019 - The Ottawa Hospital Academic Medical Organization (TOHAMO) has awarded $1.169 million in Innovation Grants to 14 teams, with supporting funds provided by the Ottawa Hospital Research Institute.
	Advances in radiation therapy improve treatment for early-stage prostate cancer January 16, 2019 - Many patients with early-stage prostate cancer now have access to shorter and more convenient courses of radiation treatment thanks in part to research at The Ottawa Hospital. The treatment, known as hypofractionated radiation therapy, delivers more
	Urologists reduce unnecessary prostate cancer surgery in Eastern Ontario July 5, 2018 - A growing number of patients in Eastern Ontario are being saved from unnecessary prostate cancer surgeries, according to a study led by Dr. Luke Lavallée and Dr. Luke Witherspoon published in CMAJ Open. While prostate cancer is the most common cancer
	Prostate cancer research gets $200,000 boost from TELUS Ride For Dad September 21, 2016 - Drs. Christina Addison, Kristopher Dennis, Jim Dimitroulakos and Luke Lavallée were awarded a combined $200,000 from the 2015 TELUS Ride For Dad to study prostate cancer from four different angles. Dr. Lavallée will establish an advanced prostate
	Immediate hormone therapy for prostate cancer is better than delayed: study September 7, 2016 - An international research team found that men with recurrent prostate cancer who received hormone treatment immediately had improved survival compared to those who delayed treatment. For many years doctors have puzzled over the best time to start a
	To treat, or not to treat? How one man decided to keep his prostate cancer June 29, 2016 - Stephen Wilson of Iroquois, Ontario avoided unnecessary treatments and side-effects by opting for regular monitoring of his slow-growing prostate cancer. Dairy plant manager Stephen Wilson faced a tough choice. In December 2012, he had just be
	Virus vs. Prostate Cancer: Canadian Researchers Pioneer Next-generation Therapy -- Prostate Cancer Canada and the Movember Foundation partner to make innovative work possible September 30, 2015 - A multi-disciplinary team of scientists and clinicians led by Dr. John Bell of The Ottawa Hospital is developing a treatment for prostate cancer using viruses that destroy cancer cells and boost the anti-cancer immune response, all the while leaving

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Addison, Christina PhD	Senior Scientist (CR)	Bone and joint degeneration, Cancer, Lung cancer, Lung disease, Pancreatic cancer, Prostate cancer, Breast cancer	Basic research, Clinical research, Cohort studies, Disease models, Drug development, Genetics, Imaging, Model organisms, Translational research, Molecular and cellular biology
Ardolino, Michele PhD	Senior Scientist (CR)	Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma	Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Breau, Rodney MD	Senior Scientist (ACR)	Cancer, Kidney disease, Prostate cancer	Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Imaging, Patient decision aids, Patient engagement, Quality Improvement, Surgery, Systematic reviews, Transfusions
Lavallee, Luke MDCM, MSc, FRCSC	Scientist (ACR)	Cancer, Kidney disease, Population health, Prostate cancer	Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health professional behaviour change, Imaging, Knowledge translation and implementation research, Patient decision aids, Quality Improvement, Surgery, Systematic reviews
Morgan, Scott MD, MSc, FRCPC	Clinician Investigator (CR)	Bladder cancer, Breast cancer, Cancer, Prostate cancer	Biomarkers, Clinical research, Clinical trials, Cohort studies, Imaging, Systematic reviews

Related Resources

Ottawa Hospital Research Institute Cancer Research Program

The Ottawa Hospital Cancer Program

Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "Prostate cancer” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

Publications

The following research publications are pulled from PubMed using the search terms "Prostate cancer" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Long-term outcomes of radiotherapy and impact of nodal disease burden in clinically node-positive prostate cancer.
2025-04-23

Evaluating the prognostic significance of artificial intelligence-delineated gross tumor volume and prostate volume measurements for prostate radiotherapy.
2025-03-22

NPV of Biparametric and Multiparametric Prostate MRI: A Comparative Systematic Review and Meta-Analysis.
2025-03-05

Association of absolute amount of pattern 4 disease on prostate biopsy with oncologic outcomes in intermediate-risk prostate cancer: A systematic review.
2025-02-24

Assessment of the benefits of bone modifying agents in the management of advanced breast, prostate, and lung cancers.
2025-02-14

Surgical Management of Genitourinary Cancer Liver Metastases.
2025-02-01

Randomized Phase II Study of Durvalumab with or without Tremelimumab in Patients with Metastatic Castration-Resistant Prostate Cancer.
2025-01-06

Optimizing Virtual Follow-Up Care: Realist Evaluation of Experiences and Perspectives of Patients With Breast and Prostate Cancer.
2025-01-03

Practice patterns and predictors of treatment intensification in patients with metastatic castration-sensitive prostate cancer.
2025-01-01

Metabolic, cardiac, and bone health testing in patients with prostate cancer on androgen-deprivation therapy: A population-based assessment of adherence to therapeutic monitoring guidelines.
2025-01-01

View more on PubMed