Cancer immunotherapy

Immunotherapy makes use of the body’s own immune system to fight cancer. This approach is revolutionizing the treatment for melanoma and several other types of cancer. The Ottawa Hospital is conducting cutting-edge research to improve our understanding of immunotherapy and develop better treatments.

Research News


Tumour engineering could provide a powerful new approach to make more cancer patients eligible for targeted immunotherapies Tumour engineering could provide a powerful new approach to make more cancer patients eligible for targeted immunotherapies
September 26, 2024 - There are many highly-effective immunotherapies available in the clinic, but few cancer patients are eligible for these treatments because their tumours must have specific targetable proteins. A new tumour engineering approach could help.
New research reveals how immunotherapy drugs and viruses can work together to kill cancer cells New research reveals how immunotherapy drugs and viruses can work together to kill cancer cells
July 5, 2024 - “These results will help guide ongoing efforts to combine checkpoint inhibitors with cancer-killing viruses in clinical trials."
Reinvigorating immunotherapy: clinical trial provides new hope for lung cancer patients Reinvigorating immunotherapy: clinical trial provides new hope for lung cancer patients
February 23, 2024 - The Ottawa Hospital played a key role in an international clinical trial that is providing new hope for people with advanced non-small cell lung cancer (NSCLC).
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Ardolino, Michele
PhD
Senior Scientist
(CR)
Blood cancer, Brain cancer, Breast cancer, Cancer, Colorectal cancer, Head and neck cancer, Liver cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Prostate cancer, Skin cancer, Soft tissue sarcoma Basic research, Cancer immunotherapy, Cell therapy, Clinical research, Disease models, Immunization, Immunotherapy, Model organisms, Molecular and cellular biology, Transgenic/knockout models, Translational research
Atkins, Harold
MD, FRCPC
Senior Clinician Investigator
(CR)
Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Cancer, Multiple sclerosis, Myasthenia gravis, Stiff person syndrome Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Immunotherapy, Oncolytic viruses, Regenerative medicine, Stem cells, Translational research, Transplantation, Viral therapy
Auer, Rebecca
MD, MSc, FRCSC
Senior Scientist
(CR)
Cancer, Colorectal cancer, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical research, Clinical trials, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Peri-operative medicine, Quality Improvement, Surgery, Translational research, Viral therapy
Bell, John
PhD, FRSC, FCAHS
Senior Scientist
(CR)
Cancer, COVID-19 Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Immunization, Immunotherapy, Oncolytic viruses, Translational research, Viral therapy
Cook, David
PhD
Scientist
(CR)
Cancer, Ovarian cancer Artificial intelligence and data science, Basic research, Big data, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Drug development, Epigenetics, Gene expression, Genomics, Imaging, Immunotherapy, Molecular and cellular biology, RNA sequencing, Systems biology, Translational research
Diallo, Jean-Simon
PhD
Senior Scientist
(CR)
Cancer, COVID-19, Infectious disease Artificial intelligence and data science, Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Druce, Irena
MD, FRCPC, MSc
Clinician Investigator
(ICD)
Diabetes, Health equity Cancer immunotherapy, Health promotion, Translational research
Ilkow, Carolina
PhD
Senior Scientist
(CR)
Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Extracellular vesicles / exosomes, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Kekre, Natasha
BSc, MD, MPH, FRCPC
Scientist
(CR)
Blood cancer, Cancer Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Clinical trials, Epidemiology, Immunotherapy, Patient engagement, Stem cells, Translational research, Transplantation, Viral therapy
Quizi, Jennifer
PhD
Investigator
(CR)
Cancer, Infectious disease Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy