Ottawa Hospital Research Institute

Research News

	Blood removal before major liver surgery cuts transfusions in half December 9, 2024 - Removing 10 per cent of a patient’s blood before major liver surgery and giving it back afterwards reduced transfusions by half, according to a large clinical trial published in The Lancet Gastroenterology & Hepatology.
	Researchers at The Ottawa Hospital awarded 14 CIHR grants worth more than $10 million July 18, 2024 - “Success at CIHR underscores the creativity, dedication and collaboration of our researchers and their teams. Funding for these innovative projects paves the way for groundbreaking advancement in biomedical sciences, improved patient care and progres
	New scientist profile: Dr. Blair Gage uses stem cell biology to build blood vessels and develop new treatments January 2, 2024 - As a self-proclaimed “cell therapist,” Dr. Blair Gage aims to understand what makes stem cells tick and then gently coax them to realize their full potential.
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	New mouse model could help with the development of treatments for nonalcoholic fatty liver disease May 29, 2021 - A surprising discovery spearheaded by MD/PhD student Dr. Marc-Olivier Deguise from Dr. Rashmi Kothary’s group could help with a better understanding of nonalcoholic fatty liver disease, a condition that affects nearly 1 billion people worldwide.
	New scientist profile: Dr. Angela Cheung’s patients inspire her to investigate rare liver diseases January 27, 2021 - Dr. Angela Cheung understands why her patients with autoimmune liver diseases are frustrated. Little is known about these rare diseases, and treatments can often only delay, but not prevent, a liver transplant.
	$950,000 to help develop stem cell treatments for septic shock, lung injury and muscle degeneration May 17, 2019 - Researchers from The Ottawa Hospital, CHEO and the University of Ottawa are bringing discoveries made in the lab closer to human trials and therapies, thanks to four new peer-reviewed research grants from the Ontario Institute for Regenerative Medici
	Clinical trials offer strong foundation for better patient care May 16, 2019 - Clinical trials are an important step toward developing new treatments and learning more about diseases and conditions. In honour of International Clinical Trials Day, read how some of the researchers at The Ottawa Hospital are making huge contribut
	The Ottawa Hospital awarded $12.7M for research, double the national CIHR success rate January 30, 2018 - Sixteen research groups at The Ottawa Hospital, affiliated with the University of Ottawa, have been awarded $12.7 million in the most recent project grant competition from the Canadian Institutes of Health Research (CIHR). This represents a success r
	Does this liver surgery patient need a blood transfusion? New tool can help doctors decide September 21, 2017 - Health care providers now have a new tool to help decide whether a liver surgery patient needs a blood transfusion, thanks to a study led by Drs. Guillaume Martel and Dean Fergusson. Liver surgery often involves major bleeding, and about one in fou
	Landmark trial could expand revolutionary treatments to all hepatitis C patients February 3, 2016 - New targeted treatments have revolutionized care for hepatitis C, offering cure rates of close to 100 percent for people infected with the most common strain of the virus. Dr. Curtis Cooper and his team have played a major role in the research th
	How does the liver affect the immune system? $175,000 grant to help find answers June 10, 2015 - Dr. Angela Crawley has been awarded a $175,000 grant from the Natural Sciences and Engineering Research Council of Canada to study how cells in the liver can influence the immune response. This project focuses on a kind of cell called a macrophage, w

Researchers

Name	Scientific appointment	Diseases, conditions and populations of interest	Research and clinical approaches
Bruni, Adrianna MSc MD CCFP-PC	Clinician Investigator (ICD)	Kidney disease, Liver disease	Palliative care
Crawley, Angela Ph.D.	Senior Scientist (ICD)	Cancer, COVID-19, Hepatitis C, HIV, Infectious disease, Liver cancer, Liver disease	Basic research, Cancer immunotherapy, Clinical research, Disease models, Immunization, Immunotherapy, Molecular and cellular biology, RNA sequencing, Translational research
Gage, Blair PhD	Scientist (RM)	Bleeding disorders, Diabetes, Liver cancer, Liver disease, Vascular, heart and metabolic disease	Basic research, Bioinformatics, Cell therapy, Disease models, Gene expression, Gene therapy, Genetics, Genomics, Model organisms, Molecular and cellular biology, Regenerative medicine, Stem cells, Translational research, Transplantation
Martel, Guillaume MD, MSc (Epi), FRCSC, FACS	Senior Scientist (ACR)	Anemia, Bleeding disorders, Colorectal cancer, Liver cancer, Liver disease, Pancreatic cancer	Anesthesiology, Clinical research, Clinical trials, Peri-operative medicine, Surgery, Systematic reviews, Transfusions
Sim, Jordan	Clinician Investigator (ICD)	Liver cancer, Liver disease

Related Resources

Liver cancer research at The Ottawa Hospital

Hepatitis C research at The  Ottawa Hospital

Search for clinical trials at The Ottawa Hospital related to this disease or condition.