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COVID-19

Researchers at The Ottawa Hospital are exploring more than 50 research projects to support the world-wide effort to find better ways to treat and prevent COVID-19. This page includes selected news stories about our COVID-19 research, links to researchers working in this area and related resources. Learn more below.

Research News


Powering up the body’s EVs
November 9, 2023 - Dr. Alvin Tieu is receiving the Worton Researcher in Training Award from The Ottawa Hospital for his multidisciplinary research on life-threatening lung diseases
Beyond the spike: novel COVID vaccine candidate targets 7 viral proteins for strong immune response
November 2, 2023 - Despite the widespread availability of COVID-19 vaccines in many countries, SARS-CoV-2 continues to spread and make people sick and new variants remain a significant threat. Researchers at The Ottawa Hospital and the University of Ottawa believe the
Obstructive sleep apnea linked with severe COVID-19
May 19, 2023 - A study led by Dr. Tetyana Kendzerska suggests that people with obstructive sleep apnea (OSA) could be at greater risk of contracting COVID-19 and having severe complications.
Show more news stories


Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Aydin, Sibel
MD
Associate Scientist
(Clinical Epidemiology)
Arthritis, Autoimmune disease, Bone and joint degeneration, COVID-19, Population health Epidemiology, Imaging
Bell, John
PhD, FRSC, FCAHS
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19 Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Immunization, Immunotherapy, Oncolytic viruses, Translational research, Viral therapy
Berardi, Philip
MD, PhD, FRCPC
Clinician Investigator
(Cancer Therapeutics)
Aging, Anemia, Bleeding disorders, Blood cancer, Cancer, COVID-19, Health equity, Health in older peoples, Sickle cell anemia, Thalassemia, Thrombosis / thromboembolism Artificial intelligence and data science, Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Immunotherapy, Molecular and cellular biology, Stem cells, Translational research
Bissell, Mary Beth
MSc, MD, FRCPC
Clinician Investigator
(Cancer Therapeutics)
Breast cancer, Cancer, COVID-19, Population health, Women's health Clinical research
Boet, Sylvain
MD, PhD
Scientist
(Clinical Epidemiology)
COVID-19 Anesthesiology, Behaviour, Clinical trials, Knowledge translation and implementation research, Patient engagement, Psychology, Qualitative methods, Quality Improvement, Surgery, Systematic reviews, Translational research
Cameron, Bill
MD FRCPC FACP FIDSA
Senior Scientist
(Clinical Epidemiology)
Chronic disease, Chronic obstructive pulmonary disease, COVID-19, Cystic fibrosis, HIV, Infectious disease, Sexually transmitted infections, Tuberculosis Clinical research, Epidemiology, Immunization, Immunotherapy, Pharmacology
Cooper, Curtis
MD, FRCPC
Scientist
(Clinical Epidemiology)
COVID-19, Hepatitis C, HIV, Infectious disease, Influenza Clinical research, Immunization
Cowan, Juthaporn
MD, PhD, FRCPC
Associate Scientist
(Clinical Epidemiology)
Autoimmune disease, COVID-19, Infectious disease Immunization, Immunotherapy, Patient engagement
Crawley, Angela
Ph.D.
Senior Scientist
(Chronic Disease)
COVID-19, Hepatitis C, HIV Basic research, Clinical research, Translational research
Diallo, Jean-Simon
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19, Infectious disease Artificial intelligence and data science, Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
El-Chaar, Darine
MD, FRCSC, Msc
Scientist
(Clinical Epidemiology)
Autoimmune disease, COVID-19, Diabetes, Infectious disease, Inflammatory bowel syndrome, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
English, Shane
MD
Senior Scientist
(Clinical Epidemiology)
COVID-19, Septic shock, Subarachnoid hemorrhage, Traumatic brain injury Clinical research, Critical care, Patient engagement
Fergusson, Dean
PhD, MHA, FCAHS
Program Director and
Senior Scientist
(Clinical Epidemiology)
Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Grimshaw, Jeremy
MBCHB, PHD
Senior Scientist
(Clinical Epidemiology)
COVID-19 Behaviour, Cluster randomized trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Qualitative methods, Quality Improvement, Surveys, Systematic reviews
Hatcher, Simon
BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych
Scientist
(Clinical Epidemiology)
Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Ilkow, Carolina
PhD
Senior Scientist
(Cancer Therapeutics)
Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Extracellular vesicles / exosomes, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Lalu, Manoj
MD, PhD, FRCPC
Scientist
(Clinical Epidemiology)
Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Manuel, Douglas
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
Mei, Shirley
PhD, MSc
Investigator
(Regenerative Medicine)
COVID-19, Septic shock Basic research, Biomarkers, Cell therapy, Critical care, Disease models, Epigenetics, Gene therapy, Knowledge translation and implementation research, Molecular and cellular biology, Regenerative medicine, Stem cells
Pakhale, Smita
MD, FRCPC, MSc (Epi & Biostat)
Senior Scientist
(Clinical Epidemiology)
COVID-19, First Nations, Inuit and Métis Health, Health equity, Health in disadvantaged peoples, Lung disease, Sickle cell anemia Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health services research, Patient engagement, Pragmatic trials, Public health, Quality Improvement
Presseau, Justin
PhD
Senior Scientist
(Clinical Epidemiology)
Chronic disease, Chronic pain, COVID-19, Diabetes, Health equity, Hepatitis C, Immigrant and refugee health, Inflammatory bowel syndrome, Retinal disease, Vision Artificial intelligence and data science, Health services research, Patient engagement, Psychometrics, Public health, Qualitative methods, Quality Improvement, Transfusions, Transplantation, Behaviour, Psychology, Health professional behaviour change, Knowledge translation and implementation research, Health promotion, Cluster randomized trials, Surveys
Seely, Andrew
MD/PhD
Scientist
(Clinical Epidemiology)
COVID-19 Artificial intelligence and data science, Critical care
Stanford, William
PhD
Senior Scientist
(Regenerative Medicine)
Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology
Stewart, Duncan
MD, FRCPC
Senior Scientist
(Regenerative Medicine)
COVID-19, Heart disease, Pulmonary hypertension, Septic shock, Vascular, heart and metabolic disease Extracellular vesicles / exosomes, Stem cells, Cell therapy, Clinical trials, Molecular and cellular biology, Regenerative medicine, Translational research
Thavorn, Kednapa
BPharm, MPharm, PhD
Senior Scientist
(Clinical Epidemiology)
Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Thiruganasambandamoorthy, Venkatesh
MBBS, CCFP-EM, MSc
Senior Scientist
(Clinical Epidemiology)
Cardiac arrest, COVID-19, Heart disease, Vascular, heart and metabolic disease Artificial intelligence and data science, Clinical decision rules, Clinical research, Emergency medicine, Epidemiology, Health services research
Tinmouth, Alan
MD, FRCPC, MSc (Clin Epi)
Senior Scientist
(Clinical Epidemiology)
COVID-19, Sickle cell anemia, Thalassemia Clinical trials, Epidemiology, Transfusions
Wilson, Kumanan
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
COVID-19, Global health, Infectious disease, Newborn and child health, Population health Artificial intelligence and data science, Big data, Biomarkers, Clinical research, Digital and mobile health, Epidemiology, Health services research, Health technology, Immunization, Public health, Transfusions, Translational research




Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "COVID-19” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCTTitleConditionStatusContact
NCT04401475A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC vs. Placebo + SOC in Adult Hospitalized Patients With COVID-19 (NCT04401475)COVID-19, ARDSRecruiting 
NCT04702945Canadian COVID-19 Emergency Department Registry (NCT04702945)Covid-19Unknown status 
NCT04865107Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial (NCT04865107)Covid19, Acute Respiratory Distress SyndromeUnknown statusdjstewart@toh.ca
NCT04500626Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 Patients (NCT04500626)Covid19Unknown statussboet@toh.on.ca, josburns@ohri.ca
NCT04894448Immunogenicity of COVID-19 Vaccination in PLWH (NCT04894448)HIV InfectionsUnknown status 
NCT05115617Pregnant and Lactating Individuals & Newborns COVID-19 Vaccination Prospective Cohort Study (NCT05115617)SARS-CoV2 Infection, Covid19, Vaccine Reaction, Pregnancy Related, ImmunogenicityRecruitingsboyd@ohri.ca, alyharvey@ohri.ca
NCT02735707Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (NCT02735707)Community-acquired Pneumonia, Influenza, COVID-19Recruiting 
NCT05513560RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine (NCT05513560)Long COVID, Post COVID Condition, Post Acute Sequelae of COVID-19Recruiting 
NCT05246098REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI (NCT05246098)Respiratory Disease, COVID-19, Viral InfectionRecruitingaseely@toh.ca
NCT04415060SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival (NCT04415060)Covid19, Hypoxic Respiratory FailureRecruitingjhaines@toh.ca, iwatpool@toh.ca
NCT05258578Tele-BARICARE to Manage COVID-19-Related Distress (NCT05258578)Obesity, Bariatric Surgery Candidate, Mental Health Disorder, Eating DisordersRecruitingdasandre@toh.ca
NCT04369690The Psychological, Social, and Economic Impacts of COVID-19 (NCT04369690)COVID-19, Chronic Disease, Psychiatric Disorder, Cardiovascular DiseasesUnknown statustkendzerska@toh.ca


Publications

The following research publications are pulled from PubMed using the search terms "COVID-19" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry.
2024-02-20

A scoping review of active, participant centred, digital adverse events following immunization (AEFI) surveillance of WHO approved COVID-19 vaccines: A Canadian immunization Research Network study.
2024-02-20

New-onset of pemphigus following COVID-19 infection: A case report.
2024-02-19

MOTIVATIONS FOR INVESTIGATING HEALTH INEQUITIES IN OBSERVATIONAL EPIDEMIOLOGY: A CONTENT ANALYSIS OF 320 STUDIES.
2024-02-19

Real-time evaluation of signal accuracy in wastewater surveillance of pathogens with high rates of mutation.
2024-02-15

Detection of Covid-19 Outbreaks Using Built Environment Testing for SARS-CoV-2.
2024-02-06

Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.
2024-02-06

Cannabis-involvement in emergency department visits for self-harm following medical and non-medical cannabis legalization.
2024-02-04

Long-term bereavement outcomes in family members of those who died in acute care hospitals before and during the first wave of COVID-19: A cohort study.
2024-01-17

A comprehensive, open-source data model for wastewater-based epidemiology.
2024-01-12

View more on PubMed