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COVID-19

Researchers at The Ottawa Hospital are exploring more than 50 research projects to support the world-wide effort to find better ways to treat and prevent COVID-19. This page includes selected news stories about our COVID-19 research, links to researchers working in this area and related resources. Learn more below.

Research News


Obstructive sleep apnea linked with severe COVID-19
May 19, 2023 - A study led by Dr. Tetyana Kendzerska suggests that people with obstructive sleep apnea (OSA) could be at greater risk of contracting COVID-19 and having severe complications.
Novel stem cell drives ‘remarkable’ regeneration of tiny blood vessels in the lung
May 15, 2023 - Dr. Duncan Stewart’s team has identified a novel stem cell with a remarkable ability to regenerate and repair the tiny blood vessels in the lungs.
COVID-19 vaccines may help reduce inappropriate use of antibiotics
May 3, 2023 - Antibiotics were commonly prescribed to older outpatients with COVID-19 in Ontario during the first two years of the pandemic, even though antibiotics do not work against the virus.
Show more news stories


Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Aydin, Sibel
MD
Associate Scientist
(Clinical Epidemiology)
Arthritis, Autoimmune disease, Bone and joint degeneration, COVID-19, Population health Epidemiology, Imaging
Bell, John
PhD, FRSC, FCAHS
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19 Basic research, Cancer biotherapeutics, Cancer immunotherapy, Cell therapy, Immunization, Immunotherapy, Oncolytic viruses, Translational research, Viral therapy
Berardi, Philip
MD, PhD, FRCPC
Clinician Investigator
(Cancer Therapeutics)
Aging, Anemia, Bleeding disorders, Blood cancer, Cancer, COVID-19, Health equity, Health in older peoples, Sickle cell anemia, Thalassemia, Thrombosis / thromboembolism Artificial intelligence and data science, Basic research, Bioinformatics, Biomarkers, Cancer biotherapeutics, Cell therapy, Epigenetics, Gene expression, Genetics, Genomics, Immunotherapy, Molecular and cellular biology, Stem cells, Translational research
Bissell, Mary Beth
MSc, MD, FRCPC
Clinician Investigator
(Cancer Therapeutics)
Breast cancer, Cancer, COVID-19, Population health, Women's health Clinical research
Boet, Sylvain
MD, PhD
Scientist
(Clinical Epidemiology)
COVID-19 Anesthesiology, Behaviour, Clinical trials, Knowledge translation and implementation research, Patient engagement, Psychology, Qualitative methods, Quality Improvement, Surgery, Systematic reviews, Translational research
Cameron, Bill
MD, FRCPC, FACP
Senior Scientist
(Clinical Epidemiology)
Chronic disease, Chronic obstructive pulmonary disease, COVID-19, Cystic fibrosis, HIV, Infectious disease, Sexually transmitted infections, Tuberculosis Clinical research, Epidemiology, Immunization, Immunotherapy, Pharmacology
Cooper, Curtis
MD, FRCPC
Scientist
(Clinical Epidemiology)
COVID-19, Hepatitis C, HIV, Infectious disease, Influenza Clinical research, Immunization
Cowan, Juthaporn
MD, PhD, FRCPC
Associate Scientist
(Clinical Epidemiology)
Autoimmune disease, COVID-19, Infectious disease Immunization, Immunotherapy, Patient engagement
Crawley, Angela
Ph.D.
Senior Scientist
(Chronic Disease)
COVID-19, Hepatitis C, HIV Basic research, Clinical research, Translational research
Diallo, Jean-Simon
PhD
Senior Scientist
(Cancer Therapeutics)
Cancer, COVID-19, Infectious disease Artificial intelligence and data science, Basic research, Cancer biotherapeutics, Cancer immunotherapy, Drug development, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
El-Chaar, Darine
MD, FRCSC, Msc
Associate Scientist
(Clinical Epidemiology)
COVID-19, Diabetes, Maternal and fetal health, Newborn and child health, Population health, Pregnancy, Women's health Clinical research, Clinical trials, Cohort studies, Epidemiology, Health research methods, Health services research, Public health, Qualitative methods, Quality Improvement, Systematic reviews
English, Shane
MD
Scientist
(Clinical Epidemiology)
COVID-19, Septic shock, Subarachnoid hemorrhage, Traumatic brain injury Clinical research, Critical care, Patient engagement
Fergusson, Dean
PhD, MHA, FCAHS
Program Director and
Senior Scientist
(Clinical Epidemiology)
Cancer, COVID-19, Kidney disease, Septic shock, Vascular, heart and metabolic disease Clinical trials, Health services research, Health technology, Patient engagement, Pragmatic trials, Surveys, Translational research, Biostatistics, Clinical research, Cluster randomized trials, Cohort studies, Critical care, Health research methods, Qualitative methods, Quality Improvement, Systematic reviews, Transfusions
Grimshaw, Jeremy
MBCHB, PHD
Senior Scientist
(Clinical Epidemiology)
COVID-19 Behaviour, Cluster randomized trials, Health professional behaviour change, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Qualitative methods, Quality Improvement, Surveys, Systematic reviews
Hatcher, Simon
BSc MBBS MMedSc MD FRCPC FRANZCP MRCPsych
Scientist
(Clinical Epidemiology)
Anxiety, Brain and neuromuscular disease, COVID-19, First Nations, Inuit and Métis Health, Health equity, Mental health, Traumatic brain injury, Depression, Health in disadvantaged peoples, Suicide Clinical research, Digital and mobile health, Health economics, Health professional behaviour change, Health research methods, Health services research, Health technology, Knowledge translation and implementation research, Patient engagement, Prevention, Public health, Qualitative methods, Clinical trials, Cluster randomized trials, Epidemiology, Psychology, Systematic reviews
Ilkow, Carolina
PhD
Senior Scientist
(Cancer Therapeutics)
Breast cancer, COVID-19, Ovarian cancer, Pancreatic cancer Basic research, Cancer biotherapeutics, Cancer immunotherapy, Extracellular vesicles / exosomes, Gene therapy, Immunization, Immunotherapy, Molecular and cellular biology, Oncolytic viruses, Translational research, Viral therapy
Lalu, Manoj
MD, PhD, FRCPC
Scientist
(Clinical Epidemiology)
Blood cancer, COVID-19, Heart disease, Stroke, Vascular, heart and metabolic disease Anesthesiology, Basic research, Cell therapy, Clinical research, Clinical trials, Disease models, Health research methods, Model organisms, Patient engagement, Regenerative medicine, Stem cells, Translational research
Manuel, Douglas
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
Aging, Alzheimer's, Cancer, COVID-19, Dementia, Diabetes, Frailty, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, Immigrant and refugee health, Infectious disease, Obesity, Parkinson's, Population health, Stroke, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Big data, Bioinformatics, Biostatistics, Digital and mobile health, Epidemiology, Health research methods, Health services research, Prevention, Public health
Mei, Shirley
PhD, MSc
Investigator
(Regenerative Medicine)
COVID-19, Septic shock Basic research, Biomarkers, Cell therapy, Critical care, Disease models, Epigenetics, Gene therapy, Knowledge translation and implementation research, Molecular and cellular biology, Regenerative medicine, Stem cells
Pakhale, Smita
MD, FRCPC, MSc (Epi & Biostat)
Senior Scientist
(Clinical Epidemiology)
COVID-19, First Nations, Inuit and Métis Health, Health equity, Health in disadvantaged peoples, Lung disease, Sickle cell anemia Clinical research, Clinical trials, Cohort studies, Epidemiology, Health economics, Health promotion, Health services research, Patient engagement, Pragmatic trials, Public health, Quality Improvement
Presseau, Justin
PhD
Senior Scientist
(Clinical Epidemiology)
COVID-19, Diabetes, Hepatitis C, Retinal disease, Vision Artificial intelligence and data science, Patient engagement, Psychometrics, Qualitative methods, Quality Improvement, Transfusions, Transplantation, Behaviour, Psychology, Health professional behaviour change, Knowledge translation and implementation research, Health promotion, Cluster randomized trials, Surveys
Seely, Andrew
MD/PhD
Scientist
(Clinical Epidemiology)
COVID-19 Artificial intelligence and data science, Critical care
Stanford, William
PhD
Senior Scientist
(Regenerative Medicine)
Aging, Blood cancer, Cancer, COVID-19, Lung cancer, Lymphangioleiomyomatosis (LAM), Vascular, heart and metabolic disease Artificial intelligence and data science, Molecular and cellular biology, Regenerative medicine, Stem cells, Systems biology
Stewart, Duncan
MD, FRCPC
Senior Scientist
(Regenerative Medicine)
COVID-19, Heart disease, Pulmonary hypertension, Septic shock, Vascular, heart and metabolic disease Extracellular vesicles / exosomes, Stem cells, Cell therapy, Clinical trials, Molecular and cellular biology, Regenerative medicine, Translational research
Tanuseputro, Peter
MD, MHSc, CCFP, FRCPC
Scientist
(Clinical Epidemiology)
Aging, Alzheimer's, COVID-19, Dementia, Health in older peoples, Population health Artificial intelligence and data science, Big data, Epidemiology, Health research methods, Health services research, Knowledge translation and implementation research, Palliative care, Public health, Risk assessment
Thavorn, Kednapa
BPharm, MPharm, PhD
Senior Scientist
(Clinical Epidemiology)
Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health equity, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Thiruganasambandamoorthy, Venkatesh
MBBS, CCFP-EM, MSc
Senior Scientist
(Clinical Epidemiology)
Cardiac arrest, COVID-19, Heart disease, Vascular, heart and metabolic disease Artificial intelligence and data science, Clinical decision rules, Clinical research, Emergency medicine, Epidemiology, Health services research
Tinmouth, Alan
MD, FRCPC, MSc (Clin Epi)
Senior Scientist
(Clinical Epidemiology)
COVID-19, Sickle cell anemia, Thalassemia Clinical trials, Epidemiology, Transfusions
Wilson, Kumanan
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
COVID-19, Global health, Infectious disease, Newborn and child health, Population health Artificial intelligence and data science, Big data, Biomarkers, Clinical research, Digital and mobile health, Epidemiology, Health services research, Health technology, Immunization, Public health, Transfusions, Translational research




Clinical Trials

The following list of clinical trials is pulled from ClinicalTrials.gov using the search terms "COVID-19” and “Ottawa Hospital.” More advanced search options are available. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. Visit ohri.ca/patients to learn more about participating in research and clinical trials.

Note that ClinicalTrials.gov is hosted by the U.S. National Library of Medicine and is only available in English. Please note that we cannot guarantee a response from the person listed in the ‘Contact’ column.

NCTTitleConditionStatusContact
NCT04401475A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC vs. Placebo + SOC in Adult Hospitalized Patients With COVID-19 (NCT04401475)COVID-19, ARDSRecruiting 
NCT04702945Canadian COVID-19 Emergency Department Registry (NCT04702945)Covid-19Recruiting 
NCT04865107Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial (NCT04865107)Covid19, Acute Respiratory Distress SyndromeUnknown statusdjstewart@toh.ca
NCT04500626Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 Patients (NCT04500626)Covid19Recruitingsboet@toh.on.ca, josburns@ohri.ca
NCT04894448Immunogenicity of COVID-19 Vaccination in PLWH (NCT04894448)HIV InfectionsRecruiting 
NCT05115617Pregnant and Lactating Individuals & Newborns COVID-19 Vaccination Prospective Cohort Study (NCT05115617)SARS-CoV2 Infection, Covid19, Vaccine Reaction, Pregnancy Related, ImmunogenicityRecruitingsboyd@ohri.ca, alyharvey@ohri.ca
NCT02735707Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (NCT02735707)Community-acquired Pneumonia, Influenza, COVID-19Recruiting 
NCT04415060SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival (NCT04415060)Covid19, Hypoxic Respiratory FailureRecruitingjhaines@toh.ca, iwatpool@toh.ca
NCT05258578Tele-BARICARE to Manage COVID-19-Related Distress (NCT05258578)Obesity, Bariatric Surgery Candidate, Mental Health Disorder, Eating DisordersRecruitingdasandre@toh.ca
NCT04369690The Psychological, Social, and Economic Impacts of COVID-19 (NCT04369690)COVID-19, Chronic Disease, Psychiatric Disorder, Cardiovascular DiseasesUnknown statustkendzerska@toh.ca
NCT04330690Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial (NCT04330690)COVID-19Recruitingsenglish@ohri.ca, iwatpool@ohri.ca, rporteous@ohri.ca


Publications

The following research publications are pulled from PubMed using the search terms "COVID-19" and "Ottawa Hospital", with publication date of 2020 or later. More advanced search options are available. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

Reliability and validity of the revised Rushton Moral Resilience Scale for healthcare workers.
2023-09-29

The barriers, facilitators and association of vaccine certificates on COVID-19 vaccine uptake: a scoping review.
2023-09-28

Prioritizing Melanoma Surgeries to Prevent Wait Time Delays and Upstaging of Melanoma during the COVID-19 Pandemic.
2023-09-27

Comparing methods to classify admitted patients with SARS-CoV-2 as admitted for COVID-19 versus with incidental SARS-CoV-2: A cohort study.
2023-09-26

Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: a double-blind randomised controlled trial.
2023-09-23

Effect of therapeutic-dose heparin on severe acute kidney injury and death in noncritically ill patients hospitalized for COVID-19: a prespecified secondary analysis of the ACTIV4a and ATTACC randomized trial.
2023-09-20

Family physicians' questions about the COVID-19 pandemic: a content analysis of 2,272 helpline calls.
2023-09-20

Derivation and External Validation of the Ottawa Bloodstream Infection Model for Acutely Ill Adults.
2023-09-19

Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness.
2023-09-18

The Intersection of the COVID-19 Pandemic and the 2021 Heat Dome in Canadian Digital News Media: A Content Analysis.
2023-09-08

View more on PubMed