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Could a drug that controls appetite also treat schizophrenia and Alzheimer’s? Mouse studies show promise.
September 8, 2021
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Two recent studies suggest that the drug trodusquemine has the potential to treat symptoms of both schizophrenia and Alzheimer’s disease. This is because the drug targets an enzyme called PTP1B, which plays a role in both diseases
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Diabetes drug corrects some symptoms of Alzheimer’s disease in mice
June 4, 2020
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A study in mice led by Dr. Jing Wang suggests that the diabetes drug metformin may be able to reverse some of the symptoms of Alzheimer's disease.
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New Frontiers in Research Fund supports trailblazing research on autism, Alzheimer’s, Parkinson’s
June 3, 2020
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Researchers from The Ottawa Hospital are involved in four new projects funded through the Exploration stream of Canada’s New Frontiers in Research Fund. The fund is designed to support high-risk, high-reward and interdisciplinary research.
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Study in mice reveals a new target to treat Alzheimer’s disease
January 23, 2020
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A new study has found that PTP1B, an enzyme that counteracts insulin and plays an important role in obesity and diabetes, is also a target for treating Alzheimer’s disease. Blocking PTP1B in mouse models of Alzheimer’s restored their spatial memory t
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Ottawa researcher plays key role in $53-million Alzheimer’s research project
September 24, 2019
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Dr. Monica Taljaard is playing a major role in a $53-million project funded by the U.S. National Institute of Aging to improve health care and quality of life for people living with Alzheimer’s disease, as well as for their caregivers.
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Brain Health Awareness Week: October 15-19
October 10, 2018
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Researchers, clinicians, patients and members of the general public are invited to take part in Brain Health Awareness Week from October 5-19, hosted by the University of Ottawa Brain and Mind Research Institute, in collaboration with The Ottawa Hosp
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Chaos in the nucleus: research on eye cells could provide insight into degenerative diseases
August 22, 2018
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The nucleus of a cell is usually a highly organized structure, with more than a metre of DNA packaged very carefully into a tiny volume. A number of degenerative diseases, including Alzheimer’s, SCA7 and progeria are associated with a breakdown in n
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Award-winning scientist challenges medical dogma in quest to prevent, treat neurodegenerative disease
October 25, 2017
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Dr. Michael Schlossmacher grew up in Austria, trained at Harvard and now leads The Ottawa Hospital’s neuroscience research program. His research helped establish a key concept in Alzheimer’s disease and led to a clinical trial of an experimental ther
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$530,000 grant to find Canadians’ most important risk factors for dementia
March 30, 2016
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Drs. Doug Manuel and Peter Tanuseputro have been awarded a $530,000 grant from the Canadian Institutes of Health Research (CIHR) to build models that will predict dementia incidence and the future burden of the disease on the Canadian population.
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