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Thrombosis / thromboembolism

The Ottawa Hospital’s Thrombosis Program is a centre of excellence in both clinical research and clinical care of thrombosis related illness. We are devoted to generating practice-changing knowledge in the areas of diagnosis, treatment and prevention of deep vein thrombosis and pulmonary embolism (venous thromboembolism).

Thrombosis Program’s Mission

The primary mission of the program is to energetically better the lives of patients with venous thromboembolic disease. This is accomplished through:

  • the design, conduct and dissemination of practice-changing clinical research
  • education of the next generation of leaders in Adult Thrombosis Medicine (expert clinicians, educators and researchers)
  • the delivery of quality cost-effective care to patients with venous thromboembolic disease in the Ottawa region

Thrombosis Program’s Vision 

It is our vision to be world leaders in developing practice-changing knowledge generation in the areas of venous thromboembolism. Our group has a strongly established presence in the development of patient-oriented research on diagnostic algorithms for suspected deep vein thrombosis and suspected pulmonary embolism and cancer-associated thrombosis. We are growing an important research program on the management of anticoagulant-related bleeding complications. We also seek to be leaders in the next generation of experts in venous thromboembolism through our Area of Focussed Competency (AFC) Adult Thrombosis Medicine Fellowship (Clinical and Research Fellowship Programs). Finally, and importantly, we seek to deliver cost-effective quality care to patients with venous thromboembolism in the Ottawa region through the development of an Ottawa Regional Clinical Thrombosis Program with arms of the program including thromboembolism management, peri-operative anticoagulation and oral anticoagulation management.

Research News


Study establishes bleeding risk with long-term use of blood thinners for life-threatening clots
October 20, 2021 - A new systematic review and meta-analysis now provides the best data yet on the long-term risks and consequences of bleeding with different blood thinners.
Full-dose blood thinners help moderately ill COVID-19 patients
August 23, 2021 - Two Canadian-led studies published in the New England Journal of Medicine show that full-dose blood thinners help moderately ill hospitalized COVID-19 patients, but not critically ill patients.
Researchers at The Ottawa Hospital awarded eight grants worth $5 million from the Canadian Institutes of Health Research
August 10, 2021 - These projects will advance science and improve health in areas such as cancer immunotherapy, orthopedic surgery, long-term care, neuromuscular disease, blood clots, vascular disease, aging, kidney disease and Inuit health.
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Researchers


Name Scientific appointment Diseases, conditions and populations of interest Research and clinical approaches
Carrier, Marc
MD, MSc, FRCPC
Senior Scientist
(Clinical Epidemiology)
Cancer, Thrombosis / thromboembolism Clinical research, Patient engagement
Castellucci, Lana
MD, FRCPC, MSc
Scientist
(Clinical Epidemiology)
Thrombosis / thromboembolism Clinical research, Clinical trials, Cohort studies, Critical care, Patient engagement, Systematic reviews, Transfusions
Duffett, Lisa
MD
Associate Scientist
(Clinical Epidemiology)
Thrombosis / thromboembolism Clinical research, Clinical trials, Epidemiology
Le Gal, Gregoire
MD, PhD
Senior Scientist
(Clinical Epidemiology)
Thrombosis / thromboembolism Clinical decision rules, Clinical research, Clinical trials, Epidemiology, Patient engagement, Peri-operative medicine
Rodger, Marc
MD
Affiliate Investigator
(Clinical Epidemiology)
Pregnancy, Thrombosis / thromboembolism, Women's health Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Epidemiology, Systematic reviews
Santos, Marlise
MD (FRCPC), MSc, MPH
Clinician Investigator
(Clinical Epidemiology)
Alzheimer's, Anxiety, Ataxia, Autoimmune disease, Autoimmune diseases of the nervous system, Blood cancer, Brain and neuromuscular disease, Brain cancer, Cancer, Chronic disease, Concussion, Dementia, Depression, Global health, Head and neck cancer, Health equity, Health in disadvantaged peoples, Infectious disease, Intellectual disabilities, Multiple sclerosis, Parkinson's, Population health, Sickle cell anemia, Spinal cord injury, Stroke, Subarachnoid hemorrhage, Thrombosis / thromboembolism, Traumatic brain injury, Traumatic injuries, Vascular cognitive impairment, Vascular, heart and metabolic disease Artificial intelligence and data science, Basic research, Behaviour, Biostatistics, Cancer biotherapeutics, Clinical decision rules, Clinical research, Clinical trials, Cohort studies, Critical care, Epidemiology, Health economics, Health research methods, Health services research, Health technology, Imaging, Patient safety, Pragmatic trials, Prevention, Public health, Qualitative methods, Quality Improvement, Shared decision making, Surgery, Surveys, Systematic reviews
Thavorn, Kednapa
BPharm, MPharm, PhD
Senior Scientist
(Clinical Epidemiology)
Cancer, COVID-19, Diabetes, Gastrointestinal disease, Glaucoma, Global health, Health in disadvantaged peoples, Health in older peoples, HIV, Immigrant and refugee health, Population health, Septic shock, Stroke, Thrombosis / thromboembolism, Vision Clinical research, Cohort studies, Epidemiology, Health economics, Health research methods, Health services research, Knowledge translation and implementation research, Patient engagement, Pharmacy, Public health, Quality Improvement, Systematic reviews
Wang, Xiang
Pharm.D, MSc, ACPR
Clinician Investigator
(Clinical Epidemiology)
Cancer, Heart disease, Population health, Stroke, Thrombosis / thromboembolism Health services research
Wells, Philip
MD, FRCPC, MSc
Senior Scientist
(Clinical Epidemiology)
Thrombosis / thromboembolism Artificial intelligence and data science, Clinical research