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MS drug boosts cancer-fighting virus in lab models
February 14, 2024
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“Immune-based therapies for cancer are showing great promise and we hope that research such as this will lead to more benefits for patients,”
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Ottawa scientist spearheads groundbreaking cancer treatments
August 18, 2023
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If you’re in the field of oncology, you’ve likely heard of Dr. Jean-Simon Diallo, an internationally recognized scientist with expertise in biochemistry, molecular biology, cancer therapeutics and viral immunology.
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From a project to a platform: A new and less expensive way to deliver immunotherapy
April 5, 2023
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Exosomes are a promising vehicle for delivering immunotherapies for many reasons. They can target specific cells or tissues, their contents are protected from degradation, there is no danger of rejection by the host, and as vehicles for cell communic
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Fireflies help researcher shine a light on COVID-19
November 2, 2022
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As a child watching fireflies in northern Iran, Dr. Taha Azad never dreamed he would someday use the secret behind their glow to help fight cancer and a global pandemic.
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Researchers at The Ottawa Hospital awarded 19 CIHR grants worth more than $12 million
July 20, 2022
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These projects will advance science and improve health in areas such as cancer, neuroscience, regenerative medicine, autism, Kabuki Syndrome, kidney disease, patient engagement, blood transfusions, sepsis, surgery, anesthesia, plasma donation, muscle
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Meet cancer researcher Dr. Taylor Jamieson-Datzkiw
April 25, 2022
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When she’s not studying to be a doctor or in the lab working on cancer-killing viruses, Métis researcher Dr. Taylor Jamieson-Datzkiw can be found mentoring the next generation of scientists and health-care providers.
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Meet HIV researcher Megan Magro
April 25, 2022
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When she’s not doing artistic swimming, Megan Magro is in the lab working towards a cure for HIV.
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Cancer-fighting viruses soften up their victims before attacking
April 7, 2022
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A research team based at The Ottawa Hospital and the University of Ottawa has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attac
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Vaccines and viral immunotherapies: unique Canadian program provides training to manufacture biotherapeutics
November 21, 2020
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As COVID-19 highlights the urgent need to increase vaccine manufacturing around the world, a unique training program is bolstering Canada’s capacity to manufacture vaccines, as well as viral immunotherapies for cancer and other emerging biotherapeuti
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From “what if” to “what is”
October 9, 2020
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What if you could deliver just one product, in this case one cancer-killing (or oncolytic) virus, to any kind of cancer and have that virus turn into something customized to kill one particular cancer –your own.
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The Ottawa Hospital and uOttawa launch new cancer immunotherapy research projects with funding from BioCanRx
September 22, 2020
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BioCanRx, Canada’s Immunotherapy Network, today announced funding of $10M for 14 cancer immunotherapy research projects and eight core and biomanufacturing facilities across the country. Researchers at The Ottawa Hospital (TOH) and the University of
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Virus and targeted drug synergize to fight cancer in mice
August 26, 2020
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While some cancer cells can be killed quickly by a single drug, the reality for patients is that multiple therapies are often required, especially if resistance develops. A new study led by Dr. Jean-Simon Diallo reveals for the first time that two pr
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Viral therapy for cancer: Frequently asked questions from patients and families
October 1, 2019
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What is viral therapy for cancer? Viral therapy for cancer, also called oncolytic viral therapy or viral immunotherapy, makes use of viruses to treat cancer.
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Dr. John Bell wins public and patient engagement award
April 15, 2019
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Dr. John Bell won the inaugural European Society for Gene and Cell Therapy Public and Patient Engagement Award.
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Researchers uncover possible new mechanism to enhance cancer-killing viruses
July 11, 2018
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Cancer-killing (oncolytic) viruses have shown promise in the lab and the clinic, but they don’t always work. New research led by Dr. Carolina Ilkow could help change this. While normal cells often lose their first line of antiviral defenses when they
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MS drug makes cancer-fighting viruses more effective in lab models
February 7, 2018
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A drug used to treat multiple sclerosis and psoriasis can dramatically enhance the spread of cancer-fighting viruses in human tumour samples and animal models, according to a study published in Science Translational Medicine. A team led by Dr. Jean
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Could viruses take cancer immunotherapy to the next level? Study shows viruses and checkpoint inhibitors work together to cure resistant breast cancer in mice
January 3, 2018
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Immunotherapy, which helps the body’s immune system attack cancer, has revolutionized treatment for cancers such as melanoma and leukemia. However, many other kinds of cancer remain resistant. A new study led by researchers at The Ottawa Hospital and
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Ottawa researchers to play lead role in new cancer immunotherapy studies
February 15, 2017
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BioCanRx funds research into CAR-T and virus-infected cell therapy
Researchers from The Ottawa Hospital and the University of Ottawa will play a lead role in cutting-edge research on cancer immunotherapy, thanks to five new peer-reviewed researc
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Virus vs. Prostate Cancer: Canadian Researchers Pioneer Next-generation Therapy
-- Prostate Cancer Canada and the Movember Foundation partner to make innovative work possible
September 30, 2015
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A multi-disciplinary team of scientists and clinicians led by Dr. John Bell of The Ottawa Hospital is developing a treatment for prostate cancer using viruses that destroy cancer cells and boost the anti-cancer immune response, all the while leaving
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Pancreatic cancer loses viral defences when talking with supporting cells
April 20, 2015
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Ottawa researchers have unlocked a way to make pancreatic cancer cells more vulnerable to cancer-killing viruses, known as oncolytic viruses. Outlined in a paper published today by Nature Medicine, the scientists have discovered how they can exploit
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Dr. Rebecca Auer awarded $450,000 to develop novel immunotherapy for pancreatic cancer
April 15, 2015
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Pancreatic cancer is one of the most deadly cancers. Surgery provides the best chance of a cure, but even then, more than 80% of patients will die of their disease. However, immunotherapies, which harness the body’s own immune system to attack cancer
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$1.2M to advance the treatment of pancreatic cancer
April 2, 2014
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The Canadian Cancer Society has awarded Dr. John Bell an Impact Grant totalling $1.2 million over the next five years to further his research into the use of viruses to fight pancreatic cancer, one of the deadliest forms of cancer. According to the
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